日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Arteriovenous metabolomics in pigs reveals CFTR regulation of metabolism in multiple organs.

猪动静脉代谢组学研究揭示了 CFTR 对多个器官代谢的调控作用

Bae Hosung, Kim Bo Ram, Jung Sunhee, Le Johnny, van der Heide Dana, Yu Wenjie, Park Sang Hee, Hilkin Brieanna M, Gansemer Nicholas D, Powers Linda S, Kang Taekyung, Meyerholz David K, Schuster Victor L, Jang Cholsoon, Welsh Michael J

Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells.

两亲性穿梭肽将碱基编辑器核糖核蛋白递送至分化良好的气道上皮细胞,以纠正 CFTR R553X 突变

Kulhankova Katarina, Cheng Anna X, Traore Soumba, Auger Maud, Pelletier Mia, Hervault Maxime, Wells Kevin D, Green Jonathan A, Byrne Addison, Nelson Benjamin, Sponchiado Mariana, Boosani Chandra, Heffner Caleb S, Snow Kathy J, Murray Stephen A, Villacreses Raul A, Rector Michael V, Gansemer Nicholas D, Stoltz David A, Allamargot Chantal, Couture Frédéric, Hemez Colin, Hallée Stéphanie, Barbeau Xavier, Harvey Mario, Lauvaux Coraline, Gaillet Bruno, Newby Gregory A, Liu David R, McCray Paul B Jr, Guay David

Mucociliary clearance is impaired in small airways of cystic fibrosis pigs

囊性纤维化猪的小气道黏液纤毛清除功能受损

Stewart, Carley G; Hilkin, Brieanna M; Gansemer, Nicholas D; Adam, Ryan J; Dick, David W; Sunderland, John J; Stoltz, David A; Zabner, Joseph; Abou Alaiwa, Mahmoud H

Mucociliary Clearance is Impaired in Small Airways of Cystic Fibrosis Pigs

囊性纤维化猪小气道黏液纤毛清除功能受损

Stewart, Carley G; Hilkin, Brieanna M; Gansemer, Nicholas D; Dick, David W; Sunderland, John J; Stoltz, David A; Abou Alaiwa, Mahmoud H; Zabner, Joseph

Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia

DNAI1突变和原发性纤毛运动障碍猪的发育和初步表征

Abou Alaiwa, Mahmoud A; Hilkin, Brie M; Price, Margaret P; Gansemer, Nicholas D; Rector, Michael R; Stroik, Mal R; Powers, Linda S; Whitworth, Kristin M; Samuel, Melissa S; Jain, Akansha; Ostedgaard, Lynda S; Ernst, Sarah E; Philibert, Winter; Boyken, Linda D; Moninger, Thomas O; Karp, Phillip H; Hornick, Douglas B; Sinn, Patrick L; Fischer, Anthony J; Pezzulo, Alejandro A; McCray, Paul B Jr; Meyerholz, David K; Zabner, Joseph; Prather, Randy S; Welsh, Michael J; Stoltz, David A

Tromethamine improves mucociliary clearance in cystic fibrosis pigs

氨丁三醇可改善囊性纤维化猪的黏液纤毛清除功能

Ash, Jamison J; Hilkin, Brieanna M; Gansemer, Nicholas D; Hoffman, Eric A; Zabner, Joseph; Stoltz, David A; Abou Alaiwa, Mahmoud H

Mucus strands from submucosal glands initiate mucociliary transport of large particles

来自黏膜下腺体的黏液丝启动大颗粒的黏液纤毛清除。

Fischer, Anthony J; Pino-Argumedo, Maria I; Hilkin, Brieanna M; Shanrock, Cullen R; Gansemer, Nicholas D; Chaly, Anna L; Zarei, Keyan; Allen, Patrick D; Ostedgaard, Lynda S; Hoffman, Eric A; Stoltz, David A; Welsh, Michael J; Alaiwa, Mahmoud H Abou

Gel-forming mucins form distinct morphologic structures in airways.

凝胶形成性粘蛋白在气道中形成独特的形态结构

Ostedgaard Lynda S, Moninger Thomas O, McMenimen James D, Sawin Nicholas M, Parker Connor P, Thornell Ian M, Powers Linda S, Gansemer Nicholas D, Bouzek Drake C, Cook Daniel P, Meyerholz David K, Abou Alaiwa Mahmoud H, Stoltz David A, Welsh Michael J

Repurposing tromethamine as inhaled therapy to treat CF airway disease

将氨丁三醇重新用于吸入疗法以治疗囊性纤维化气道疾病

Abou Alaiwa, Mahmoud H; Launspach, Janice L; Sheets, Kelsey A; Rivera, Jade A; Gansemer, Nicholas D; Taft, Peter J; Thorne, Peter S; Welsh, Michael J; Stoltz, David A; Zabner, Joseph

The role of Rabconnectin3a in cilia length regulation

Rabconnectin3a在纤毛长度调控中的作用

Pino-Argumedo, Maria I; Fischer, Anthony J; Hilkin, Brieanna M; Gansemer, Nicholas D; Allen, Patrick D; Hoffman, Eric A; Stoltz, David A; Welsh, Michael J; Abou Alaiwa, Mahmoud H; Tavares, B; Pintado, P; Lopes, SS