日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

RNA G-Quadruplexes Function as a Tunable Switch of FUS Phase Separation.

RNA G-四链体作为FUS相分离的可调开关。

Carey Jenny L, Hayashi Miyuki, Welebob Emily, Ganser Laura R, Wang Huan, Buckhaults Kerry, DePierro Jacquelyn A, Shi Zheng, Shorter James, Myong Sua, Haeusler Aaron R, Guo Lin

The roles of FUS-RNA binding domain and low complexity domain in RNA-dependent phase separation.

FUS-RNA结合域和低复杂度域在RNA依赖性相分离中的作用

Ganser Laura R, Niaki Amirhossein Ghanbari, Yuan Xincheng, Huang Ethan, Deng Dahlia, Djaja Nathalie A, Ge Yingda, Craig Alanna, Langlois Olivia, Myong Sua

RNA conformational propensities determine cellular activity

RNA构象倾向决定细胞活性

Ken, Megan L; Roy, Rohit; Geng, Ainan; Ganser, Laura R; Manghrani, Akanksha; Cullen, Bryan R; Schulze-Gahmen, Ursula; Herschlag, Daniel; Al-Hashimi, Hashim M

Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem-loop RNAs and their implications for functional cellular assays

了解类药化合物与典型茎环RNA的非特异性结合特征及其对功能性细胞分析的影响

Kelly, Megan L; Chu, Chia-Chieh; Shi, Honglue; Ganser, Laura R; Bogerd, Hal P; Huynh, Kelly; Hou, Yuze; Cullen, Bryan R; Al-Hashimi, Hashim M

Probing RNA Conformational Equilibria within the Functional Cellular Context.

在功能性细胞环境中探测RNA构象平衡

Ganser Laura R, Chu Chia-Chieh, Bogerd Hal P, Kelly Megan L, Cullen Bryan R, Al-Hashimi Hashim M

Demonstration that Small Molecules can Bind and Stabilize Low-abundance Short-lived RNA Excited Conformational States

证明小分子可以结合并稳定低丰度、短寿命的RNA激发态构象

Ganser, Laura R; Kelly, Megan L; Patwardhan, Neeraj N; Hargrove, Amanda E; Al-Hashimi, Hashim M

The roles of structural dynamics in the cellular functions of RNAs

结构动力学在RNA细胞功能中的作用

Ganser, Laura R; Kelly, Megan L; Herschlag, Daniel; Al-Hashimi, Hashim M

High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble

通过靶向高分辨率RNA动态集合进行高性能虚拟筛选

Ganser, Laura R; Lee, Janghyun; Rangadurai, Atul; Merriman, Dawn K; Kelly, Megan L; Kansal, Aman D; Sathyamoorthy, Bharathwaj; Al-Hashimi, Hashim M

Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics

解析RNA激发态中的糖环褶皱揭示了缓慢的重褶皱动力学模式

Clay, Mary C; Ganser, Laura R; Merriman, Dawn K; Al-Hashimi, Hashim M