日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Macrophage PRMT9 Ameliorates Acute Myocardial Infarction by Promoting Symmetric Dimethylation and Degradation of STAT1

巨噬细胞PRMT9通过促进STAT1的对称二甲基化和降解来改善急性心肌梗死。

期刊:Circulation
影响因子:38.6
doi:10.1161/CIRCULATIONAHA.125.076101
Bai, Xuemei; Ren, Ruiqing; Yuan, Jiahua; Yu, Liwen; Dong, Na; Cao, Nan; Zhou, Min; Zhang, JiaJia; Li, Xiaoxiao; He, Ziye; Liu, Bingyu; Zhang, Meng; Gao, Chengjiang
巨噬细胞
STAT1
表观遗传
JAK/STAT
巨噬细胞
心血管
细胞生物学
心肌梗塞
免疫/内分泌
发表日期：2026
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The Crohn's disease-related RNF123 prevents NLRP3 inflammasome assembly by catalyzing unanchored K63-linked ubiquitination on NEK7

与克罗恩病相关的RNF123通过催化NEK7上非锚定K63连接的泛素化来阻止NLRP3炎症小体的组装。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2518759123
Liu, Feng; Zhuang, Wanxin; Yang, Yuan; Zhao, Wenting; Li, Siyuan; Zhang, Ziyue; Liu, Yifan; Liu, Bingyu; Qi, Xiaopeng; Zhao, Wei; Da, Lintai; Gao, Chengjiang
炎性小体
发表日期：2026
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SCD1 licenses STING signaling through fatty acid desaturation-mediated membrane remodeling

SCD1通过脂肪酸去饱和介导的膜重塑激活STING信号通路

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2528843123
Qin, Danhui; Gao, Yanjie; Jiang, Haojia; Meng, Xintong; Qin, Ying; Song, Hui; Fu, Yue; Gao, Chengjiang; Jia, Mutian; Zhao, Chunyuan; Zhao, Wei
代谢
信号转导
STING
SCD
发表日期：2026
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Histone demethylase KDM4B epigenetically controls NLRP3 expression to enhance inflammatory responses.

组蛋白去甲基化酶 KDM4B 通过表观遗传学控制 NLRP3 的表达，从而增强炎症反应。

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.1038/s44321-026-00373-0
Tong Li, Song Hui, Gao Yuan, Qin Danhui, Wang Caiwei, Li Qi, Fu Yue, Zhao Chunyuan, Ying Zhendong, Chen Dailing, Gao Chengjiang, Han Chaofeng, Zhao Wei, Qin Ying, Zhang Lei
炎症
表观遗传
炎症/感染
LRP3
NLRP3
发表日期：2026
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ZNF593 regulates the cGAS-mediated innate immune response by attenuating cGAS-DNA binding.

ZNF593 通过减弱 cGAS-DNA 结合来调节 cGAS 介导的先天免疫反应

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-025-01508-5
Bai Xuemei, Dong Na, Cao Nan, Zhou Min, Yuan Jiahua, Zhang Yuling, Liu Yaxing, Zhang JiaJia, Chen Tian, Liu Feng, Sun Wanwei, Zheng Yi, Zhao Wei, Shu Qiang, Gao Chengjiang, Liu Bingyu
其它
发表日期：2025
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The protein arginine methyltransferase PRMT1 ameliorates cerebral ischemia-reperfusion injury by suppressing RIPK1-mediated necroptosis and apoptosis

蛋白质精氨酸甲基转移酶PRMT1通过抑制RIPK1介导的坏死性凋亡和细胞凋亡来减轻脑缺血再灌注损伤。

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.06.005
Liu, Tengfei; Huang, Gan; Guo, Xin; Ji, Qiuran; Yu, Lu; Zong, Runzhe; Li, Yiquan; Song, Xiaomeng; Fu, Qingyi; Xue, Qidi; Zheng, Yi; Zeng, Fanshuo; Sun, Ru; Chen, Lin; Gao, Chengjiang; Liu, Huiqing
凋亡
表观遗传
神经科学
PRMT1
细胞生物学
RIP
发表日期：2025
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Listerin Alleviates Alzheimer's Disease through IRE1-mediated Decay of TLR4 mRNA.

李施德林通过IRE1介导的TLR4 mRNA降解来缓解阿尔茨海默病

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202414956
Qin Fei, Cao Runyu, Bai Xuemei, Yuan Jiahua, Sun Wanwei, Zheng Yi, Qi Xiaopeng, Zhao Wei, Liu Bingyu, Gao Chengjiang
其它
发表日期：2025
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E3 ubiquitin ligase Listerin regulates macrophage cholesterol efflux and atherosclerosis by targeting ABCA1

E3泛素连接酶Listerin通过靶向ABCA1调节巨噬细胞胆固醇外流和动脉粥样硬化。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI186509
Cao, Lei; Zhang, Jie; Yu, Liwen; Yang, Wei; Qi, Wenqian; Ren, Ruiqing; Liu, Yapeng; Hou, Yonghao; Cao, Yu; Li, Qian; Wang, Xiaohong; Zhang, Zhengguo; Li, Bo; Sui, Wenhai; Zhang, Yun; Gao, Chengjiang; Zhang, Cheng; Zhang, Meng
巨噬细胞
ABCA1
巨噬细胞
心血管
代谢
细胞生物学
动脉粥样硬化
免疫/内分泌
发表日期：2025
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AGR2-mediated cell-cell communication controls the antiviral immune response by promoting the thiol oxidation of TRAF3.

AGR2介导的细胞间通讯通过促进TRAF3的硫醇氧化来控制抗病毒免疫反应

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103581
Jia Mengqi, Chen Xiaojing, Guo Wenxue, Ma Dapeng, Wang Peng, Niu Huanmin, Liu Changhong, Lin Xianjuan, Lu QiQi, Wang Jing, Zheng Xiaoxue, Sun Qi, Gao Chengjiang, Yuan Huiqing
细胞生物学
Viral
发表日期：2025
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E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model

E3泛素连接酶TRIM31通过促进帕金森病模型中VDAC1的蛋白酶体降解来缓解多巴胺能神经退行性变

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-024-01334-1
Zhao, Ze; Song, Xiaomeng; Wang, Yimeng; Yu, Lu; Huang, Gan; Li, Yiquan; Zong, Runzhe; Liu, Tengfei; Ji, Qiuran; Zheng, Yi; Liu, Bingyu; Zhu, Qingfen; Chen, Lin; Gao, Chengjiang; Liu, Huiqing
VDAC1
帕金森
神经科学
发表日期：2024
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