日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function

未结合的IgG Fc受体CD64的溶液结构与其晶体结构相似:对功能的影响

Hui, Gar Kay; Gao, Xin; Gor, Jayesh; Lu, Jinghua; Sun, Peter D; Perkins, Stephen J

The solution structure of the human IgG2 subclass is distinct from those for human IgG1 and IgG4 providing an explanation for their discrete functions

人IgG2亚类的溶液结构与人IgG1和IgG4的溶液结构截然不同,这解释了它们各自不同的功能。

Hui, Gar Kay; Gardener, Antoni D; Begum, Halima; Eldrid, Charles; Thalassinos, Konstantinos; Gor, Jayesh; Perkins, Stephen J

Atomistic Modeling of Scattering Curves for Human IgG1/4 Reveals New Structure-Function Insights

人IgG1/4散射曲线的原子级建模揭示了新的结构-功能关系

Wright, David W; Elliston, Emma L K; Hui, Gar Kay; Perkins, Stephen J

The solution structures of native and patient monomeric human IgA1 reveal asymmetric extended structures: implications for function and IgAN disease

天然和患者单体人IgA1的溶液结构揭示了不对称的延伸结构:对功能和IgAN疾病的启示

Hui, Gar Kay; Wright, David W; Vennard, Owen L; Rayner, Lucy E; Pang, Melisa; Yeo, See Cheng; Gor, Jayesh; Molyneux, Karen; Barratt, Jonathan; Perkins, Stephen J

The solution structures of two human IgG1 antibodies show conformational stability and accommodate their C1q and FcγR ligands

两种人IgG1抗体的溶液结构显示出构象稳定性,并能容纳其C1q和FcγR配体。

Rayner, Lucy E; Hui, Gar Kay; Gor, Jayesh; Heenan, Richard K; Dalby, Paul A; Perkins, Stephen J

The Fab conformations in the solution structure of human immunoglobulin G4 (IgG4) restrict access to its Fc region: implications for functional activity

人类免疫球蛋白 G4 (IgG4) 溶液结构中的 Fab 构象限制了对其 Fc 区的访问:对功能活性的影响

Lucy E Rayner, Gar Kay Hui, Jayesh Gor, Richard K Heenan, Paul A Dalby, Stephen J Perkins