日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel neurofilament light (Nefl) E397K mouse models of Charcot-Marie-Tooth type 2E (CMT2E) present early and chronic axonal neuropathy

新型神经丝轻链(Nefl)E397K小鼠模型(夏科-马里-图斯病2E型(CMT2E))表现出早期和慢性轴突神经病变

Pérez-López, Dennis O; Shively, Audrey A; Torres, F Javier Llorente; Abu-Salah, Mohammed T; Garcia, Michael L; Arnold, W David; Lorson, Monique A; Lorson, Christian L

The Nefl (E397K) mouse model demonstrates muscle pathology and motor function deficits consistent with CMT2E.

Nefl (E397K) 小鼠模型表现出与 CMT2E 一致的肌肉病理和运动功能缺陷

Pérez-López Dennis O, Shively Audrey A, Torres F Javier Llorente, Muchow Roxanne, Abu-Salah Zaid, Abu-Salah Mohammed T, Garcia Michael L, Smith Catherine L, Nichols Nicole L, Lorson Monique A, Lorson Christian L

Lumbar spinal cord microglia exhibited increased activation in aging dogs compared with young adult dogs

与年轻成年犬相比,老年犬腰椎脊髓小胶质细胞的激活程度更高。

Toedebusch, Christine M; Garcia, Virginia B; Snyder, John C; Jones, Maria R; Schulz, David J; Johnson, Gayle C; Villalón, Eric; Coates, Joan R; Garcia, Michael L

Internode length is reduced during myelination and remyelination by neurofilament medium phosphorylation in motor axons

在运动轴突中,神经丝中层磷酸化导致髓鞘形成和髓鞘再生过程中节间长度缩短。

Villalón, Eric; Barry, Devin M; Byers, Nathan; Frizzi, Katie; Jones, Maria R; Landayan, Dan S; Dale, Jeffrey M; Downer, Natalie L; Calcutt, Nigel A; Garcia, Michael L

Placental development in a mouse model of spinal muscular atrophy

脊髓性肌萎缩症小鼠模型中的胎盘发育

Van Gronigen Caesar, Gerialisa; Dale, Jeffrey M; Osman, Erkan Y; Garcia, Michael L; Lorson, Christian L; Schulz, Laura C

X-linked spinal muscular atrophy in mice caused by autonomous loss of ATP7A in the motor neuron

小鼠X连锁脊髓性肌萎缩症是由运动神经元中ATP7A的自主性缺失引起的

Hodgkinson, Victoria L; Dale, Jeffery M; Garcia, Michael L; Weisman, Gary A; Lee, Jaekwon; Gitlin, Jonathan D; Petris, Michael J

Axonal transport: how high microtubule density can compensate for boundary effects in small-caliber axons

轴突运输:高微管密度如何补偿小口径轴突中的边界效应

Wortman, Juliana C; Shrestha, Uttam M; Barry, Devin M; Garcia, Michael L; Gross, Steven P; Yu, Clare C

The spinal muscular atrophy mouse model, SMAΔ7, displays altered axonal transport without global neurofilament alterations

脊髓性肌萎缩症小鼠模型SMAΔ7表现出轴突运输改变,但无整体神经丝改变。

Dale, Jeffrey M; Shen, Hailian; Barry, Devin M; Garcia, Virginia B; Rose, Ferrill F Jr; Lorson, Christian L; Garcia, Michael L

Muscle pathology without severe nerve pathology in a new mouse model of Charcot-Marie-Tooth disease type 2E

在一种新的夏科-马里-图斯病2E型小鼠模型中,肌肉病变而无严重的神经病变。

Shen, Hailian; Barry, Devin M; Dale, Jeffrey M; Garcia, Virginia B; Calcutt, Nigel A; Garcia, Michael L

Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice

在运动神经元和少突胶质细胞以外的其他细胞类型中,突变型SOD1会加速ALS小鼠疾病的发生。

Yamanaka, Koji; Boillee, Severine; Roberts, Elizabeth A; Garcia, Michael L; McAlonis-Downes, Melissa; Mikse, Oliver R; Cleveland, Don W; Goldstein, Lawrence S B