NF-κB and TET2 promote macrophage reprogramming in hypoxia that overrides the immunosuppressive effects of the tumor microenvironment
NF-κB和TET2在缺氧条件下促进巨噬细胞重编程,从而克服肿瘤微环境的免疫抑制作用。
期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.adq5226
Carlos de la Calle-Fabregat ,Josep Calafell-Segura ,Margaux Gardet ,Garett Dunsmore ,Kevin Mulder ,Laura Ciudad ,Aymeric Silvin ,Joaquim Moreno-Càceres ,Ángel L Corbí ,Cristina Muñoz-Pinedo ,Judith Michels ,Sébastien Gouy ,Charles-Antoine Dutertre ,Javier Rodríguez-Ubreva ,Florent Ginhoux ,Esteban Ballestar
免疫/内分泌
NF-κB
发育与干细胞
肿瘤免疫
肿瘤微环境
细胞生物学
巨噬细胞
巨噬细胞
肿瘤
TET2