Gardner Brooke M相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

The FANCD2-FANCI heterodimer coordinates chromatin openness and cell cycle progression throughout DNA double-strand break repair.

FANCD2-FANCI 异二聚体在 DNA 双链断裂修复过程中协调染色质开放和细胞周期进程。

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2025.116830

Joyce Christine M, Bacal Julien, Chowdhury Soham P, Brown Andrew N, Wang Amy K, Cruz Carmen, Bains Kameron, Rodriguez Zachary N, McCormick Nathan J, Tzadikario Yaara, Tavasoli Katherine U, Gardner Brooke M, Richardson Chris D

细胞生物学

发表日期：2026

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SFPQ Promotes Homologous Recombination via mRNA Stabilization of RAD51 and Its Paralogs

SFPQ通过稳定RAD51及其旁系同源基因的mRNA促进同源重组

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2026.169677

Gotthold, Sofia; Hansen, Keile R; Brown, Andrew N; Chowdhury, Soham P; Joyce, Christine M; Vinish, Viraj; Rodriguez, Sofie I; Jain, Sambhav; Ghasemi, Hannah I; Yoon, Amanda C; Bacal, Julien; Morrissey, Meghan A; Gardner, Brooke M; Richardson, Chris D

发表日期：2026

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CD47 inhibits phagocytosis through Vav dephosphorylation.

CD47 通过 Vav 去磷酸化抑制吞噬作用。

期刊:Journal of Cell Biology

影响因子:6.4

doi:10.1083/jcb.202502206

Miller Wyatt D, Manion Andrew, Mishra Abhinava K, Sheedy Connor J, Bond Annalise, Gardner Brooke M, Montell Denise J, Morrissey Meghan A

发表日期：2025

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PEX1(G843D) remains functional in peroxisome biogenesis but is rapidly degraded by the proteasome.

PEX1(G843D)在过氧化物酶体生物合成中仍具有功能，但会被蛋白酶体迅速降解

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.108467

Sheedy Connor J, Chowdhury Soham P, Ali Bashir A, Miyamoto Julia, Pang Eric Z, Bacal Julien, Tavasoli Katherine U, Richardson Chris D, Gardner Brooke M

发表日期：2025

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SFPQ Promotes Homologous Recombination via mRNA Stabilization of RAD51 and Its Paralogs

SFPQ通过稳定RAD51及其旁系同源基因的mRNA促进同源重组

doi:10.1101/2025.09.08.674956

Gotthold, Sofia; Hansen, Keile R; Brown, Andrew N; Chowdhury, Soham P; Ghasemi, Hannah I; Yoon, Amanda C; Joyce, Christine M; Bacal, Julien; Gardner, Brooke M; Richardson, Chris D

发表日期：2025

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Insights into the Structure and Function of the Pex1/Pex6 AAA-ATPase in Peroxisome Homeostasis

深入了解过氧化物酶体稳态中 Pex1/Pex6 AAA-ATPase 的结构和功能

影响因子:5.2

doi:10.3390/cells11132067

Judy, Ryan M; Sheedy, Connor J; Gardner, Brooke M

发表日期：2022

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Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling

撤稿声明：未折叠蛋白反应元件IRE1α感知入侵内质网的细菌蛋白以激活RIG-I和先天免疫信号传导

期刊:Cell Host & Microbe

影响因子:18.7

doi:10.1016/j.chom.2018.03.005

Cho, Jin A; Lee, Ann-Hwee; Platzer, Barbara; Cross, Benedict C S; Gardner, Brooke M; De Luca, Heidi; Luong, Phi; Harding, Heather P; Glimcher, Laurie H; Walter, Peter; Fiebiger, Edda; Ron, David; Kagan, Jonathan C; Lencer, Wayne I

免疫/内分泌

发表日期：2018

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The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading.

过氧化物酶体 AAA-ATPase Pex1/Pex6 通过连续穿线的方式展开底物

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-017-02474-4

Gardner Brooke M, Castanzo Dominic T, Chowdhury Saikat, Stjepanovic Goran, Stefely Matthew S, Hurley James H, Lander Gabriel C, Martin Andreas

发表日期：2018

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The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling

未折叠蛋白反应元件IRE1α能够感知入侵内质网的细菌蛋白，从而激活RIG-I和先天免疫信号通路。

期刊:Cell Host & Microbe

影响因子:18.7

doi:10.1016/j.chom.2013.03.011

Cho, Jin A; Lee, Ann-Hwee; Platzer, Barbara; Cross, Benedict C S; Gardner, Brooke M; De Luca, Heidi; Luong, Phi; Harding, Heather P; Glimcher, Laurie H; Walter, Peter; Fiebiger, Edda; Ron, David; Kagan, Jonathan C; Lencer, Wayne I

免疫/内分泌

发表日期：2013

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