日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression

SigH 应激反应通过诱导 Mrx2 表达激活硝基萘并呋喃前药来介导杀死结核分枝杆菌

Laura Cioetto-Mazzabò, Francesca Boldrin, Claire Beauvineau, Martin Speth, Alberto Marina, Amine Namouchi, Greta Segafreddo, Mena Cimino, Sandrine Favre-Rochex, Seetha Balasingham, Beatriz Trastoy, Hélène Munier-Lehmann, Gareth Griffiths, Brigitte Gicquel, Marcelo E Guerin, Riccardo Manganelli, Noel

SARS-CoV-2 infection risk among 77,587 healthcare workers: a national observational longitudinal cohort study in Wales, United Kingdom, April to November 2020

2020年4月至11月,英国威尔士77587名医护人员SARS-CoV-2感染风险:一项全国性观察性纵向队列研究

Hollinghurst, Joe; North, Laura; Szakmany, Tamas; Pugh, Richard; Davies, Gwyneth A; Sivakumaran, Shanya; Jarvis, Rebecca; Rolles, Martin; Pickrell, W Owen; Akbari, Ashley; Davies, Gareth; Griffiths, Rowena; Lyons, Jane; Torabi, Fatemeh; Fry, Richard; Gravenor, Mike B; Lyons, Ronan A

The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds

斑马鱼胚胎作为筛选纳米颗粒配方亲脂性抗结核化合物的体内模型

Nils-Jørgen Knudsen Dal, Martin Speth, Kerstin Johann, Matthias Barz, Claire Beauvineau, Jens Wohlmann, Federico Fenaroli, Brigitte Gicquel, Gareth Griffiths, Noelia Alonso-Rodriguez

Development and Application of High-Content Biological Screening for Modulators of NET Production

NET 生成调节剂的高内涵生物筛选的开发和应用

Ilaria J Chicca, Michael R Milward, Iain Leslie C Chapple, Gareth Griffiths, Rod Benson, Thomas Dietrich, Paul R Cooper

Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells

邻苯二酚二霉菌酸酯促进结核分枝杆菌进入淋巴管内皮细胞的胞质溶胶并增加其胞内载量。

Thomas R Lerner,Christophe J Queval,Antony Fearns,Urska Repnik,Gareth Griffiths,Maximiliano G Gutierrez

High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma

对患者来源的细胞系进行高内涵筛选,凸显了非标准化疗药物治疗胶质母细胞瘤的潜力

Kenny Kwok-Hei Yu, Jessica T Taylor, Omar N Pathmanaban, Amir Saam Youshani, Deniz Beyit, Joanna Dutko-Gwozdz, Roderick Benson, Gareth Griffiths, Ian Peers, Peter Cueppens, Brian A Telfer, Kaye J Williams, Catherine McBain, Ian D Kamaly-Asl, Brian W Bigger

Co-culture of human alveolar epithelial (hAELVi) and macrophage (THP-1) cell lines

人类肺泡上皮细胞 (hAELVi) 和巨噬细胞 (THP-1) 细胞系共培养

Stephanie Kletting, Sarah Barthold, Urska Repnik, Gareth Griffiths, Brigitta Loretz, Nicole Schneider-Daum, Cristiane de Souza Carvalho-Wodarz, Claus-Michael Lehr

Mycobacterium tuberculosis replicates within necrotic human macrophages

结核分枝杆菌在坏死的人类巨噬细胞内复制

Thomas R Lerner, Sophie Borel, Daniel J Greenwood, Urska Repnik, Matthew R G Russell, Susanne Herbst, Martin L Jones, Lucy M Collinson, Gareth Griffiths, Maximiliano G Gutierrez

Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis

淋巴管内皮细胞是结核分枝杆菌的复制生态位

Thomas R Lerner, Cristiane de Souza Carvalho-Wodarz, Urska Repnik, Matthew R G Russell, Sophie Borel, Collin R Diedrich, Manfred Rohde, Helen Wainwright, Lucy M Collinson, Robert J Wilkinson, Gareth Griffiths, Maximiliano G Gutierrez

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

脂肪细胞通过非经典途径分泌脂肪酸结合蛋白aP2,以响应脂肪细胞脂肪酶活性

Meric Erikci Ertunc, Jørgen Sikkeland, Federico Fenaroli, Gareth Griffiths, Mathew P Daniels, Haiming Cao, Fahri Saatcioglu, Gökhan S Hotamisligil