日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Host Prior Exposure Augments Gene Expression Heterogeneity of Both Host and Pathogen During In Vivo Infection

宿主既往暴露会增强体内感染过程中宿主和病原体的基因表达异质性

Pérez-Umphrey, Anna A; Miller, Jeremy; Tulman, Edan R; Garrett-Larsen, Jesse; Vinkler, Michal; Langwig, Kate; Geary, Steven J; Adelman, James S; Hawley, Dana M

Reinfection with a Bacterial Pathogen Augments Heterogeneity in Host Disease Responses

细菌病原体的再次感染会加剧宿主疾病反应的异质性

Garrett-Larsen, Jesse; Pérez-Umphrey, Anna; Fleming-Davies, Arietta; Adelman, James; Childs, Lauren; Geary, Steven; Langwig, Kate; Hawley, Dana

Host prior exposure augments heterogeneity in gene expression in both host and pathogen during in vivo infection

宿主先前的感染经历会增强体内感染过程中宿主和病原体基因表达的异质性。

Pérez-Umphrey, Anna A; Miller, Jeremy; Tulman, Edan R; Garrett-Larsen, Jesse; Vinkler, Michal; Langwig, Kate; Geary, Steven J; Adelman, James S; Hawley, Dana M

Infected host competence overshadows heterogeneity in susceptibility in shaping experimental epizootics

在塑造实验性动物流行病的过程中,受感染宿主的感染能力掩盖了易感性的异质性。

Pérez-Umphrey, Anna A; Langwig, Kate E; Adelman, James S; Childs, Lauren M; Garrett-Larsen, Jesse; Hawley, Dana M; Fleming-Davies, Arietta E

Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.

将 IL-12 mRNA 纳米技术与 SBRT 相结合,可消除胰腺癌临床前模型中的 T 细胞耗竭

Hughson Angela L, Hannon Gary, Salama Noah A, Vrooman Tara G, Stockwell Caroline A, Mills Bradley N, Garrett-Larsen Jesse, Qiu Haoming, Katerji Roula, Benoodt Lauren, Johnston Carl J, Murphy Joseph D, Kruger Emma, Ye Jian, Gavras Nicholas W, Keeley David C, Qin Shuyang S, Lesch Maggie L, Muhitch Jason B, Love Tanzy M T, Calvi Laura M, Lord Edith M, Luheshi Nadia, Elyes Jim, Linehan David C, Gerber Scott A

Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences

既往接触病原体会增加宿主易感性的异质性,并产生重要的流行病学后果。

Hawley, Dana M; Pérez-Umphrey, Anna A; Adelman, James S; Fleming-Davies, Arietta E; Garrett-Larsen, Jesse; Geary, Steven J; Childs, Lauren M; Langwig, Kate E

New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy

直肠癌治疗应答者/无应答者差异的新见解:损伤诱导的I型干扰素决定治疗效果,可作为靶点增强放射治疗效果

Uccello, Taylor P; Lesch, Maggie L; Kintzel, Sarah A; Gradzewicz, Lauren B; Lamrous, Lillia; Murphy, Shawn P; Fleming, Fergal J; Mills, Bradley N; Murphy, Joseph D; Hughson, Angela; Hannon, Gary; Garrett-Larsen, Jesse; Qiu, Haoming; Drage, Michael G; Ye, Jian; Gavras, Nicholas W; Keeley, David C; Love, Tanzy M T; Repasky, Elizabeth A; Lord, Edith M; Linehan, David C; Gerber, Scott A

Radiation Therapy Exacerbates Tumor-Promoting Innervation and Nerve Signaling in Rectal Cancer

放射治疗会加剧直肠癌中促进肿瘤生长的神经支配和神经信号传导

Uccello, Taylor P; Lesch, Maggie L; Ullman, Nicholas A; Kintzel, Sarah A; Gradzewicz, Lauren B; Velagaleti, Trishna; Fleming, Fergal J; Mills, Bradley N; Murphy, Joseph D; Garrett-Larsen, Jesse; Qiu, Haoming; Drage, Michael G; Ye, Jian; Gavras, Nicholas W; Johnston, Carl J; Love, Tanzy M T; Repasky, Elizabeth A; Linehan, David C; Lord, Edith M; Gerber, Scott A

Development of an Orthotopic Murine Model of Rectal Cancer in Conjunction With Targeted Short-Course Radiation Therapy

建立直肠癌原位小鼠模型并结合靶向短期放射治疗

Uccello, Taylor P; Kintzel, Sarah A; Mills, Bradley N; Murphy, Joseph D; Garrett-Larsen, Jesse; Battaglia, Nicholas G; Rodriguez, Carlos J; Drage, Michael G; Ye, Jian; Love, Tanzy M T; Johnston, Carl J; Repasky, Elizabeth A; Qiu, Haoming; Linehan, David C; Lord, Edith M; Gerber, Scott A

Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma.

包裹免疫治疗药物的微球靶向胰腺导管腺癌的肿瘤引流淋巴结

Han Booyeon J, Murphy Joseph D, Qin Shuyang, Ye Jian, Uccello Taylor P, Garrett-Larsen Jesse, Belt Brian A, Prieto Peter A, Egilmez Nejat K, Lord Edith M, Linehan David C, Mills Bradley N, Gerber Scott A