CAR-T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment
与复发时或接受达雷妥尤单抗治疗后产生的CAR-T细胞相比,从多发性骨髓瘤患者确诊时获得的CAR-T细胞具有更强的细胞毒性功能。
期刊:eJHaem
影响因子:1.2
doi:10.1002/jha2.479
Abecassis, Audrey; Roders, Nathalie; Fayon, Maxime; Choisy, Caroline; Nelson, Elisabeth; Harel, Stephanie; Royer, Bruno; Villesuzanne, Camille; Talbot, Alexis; Garrick, David; Goodhardt, Michele; Fermand, Jean-Paul; Burbridge, Mike; Arnulf, Bertrand; Bories, Jean-Christophe
T细胞
多发性骨髓瘤
T细胞
骨髓瘤
细胞生物学
毒理研究
免疫/内分泌