日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The long non-coding RNA CRNDE stabilises SIRT1 protein and influences Hedgehog signalling in multiple myeloma

长链非编码RNA CRNDE可稳定SIRT1蛋白并影响多发性骨髓瘤中的Hedgehog信号通路。

Zocchi, Simone; Trichet, Pauline; Guernalec, Paloma; Agdada, Manal; Alonso Bartolomé, Ana; Ogor, Vincent; Choisy, Caroline; Vias, Carine; Sabaté-Cadenas, Xavier; Bories, Jean-Christophe; Goodhardt, Michele; Shkumatava, Alena; Garrick, David

Transcriptomic characterisation of acute myeloid leukemia cell lines bearing the same t(9;11) driver mutation reveals different molecular signatures.

对携带相同 t(9;11) 驱动突变的急性髓系白血病细胞系进行转录组学表征,揭示了不同的分子特征

Georges Elise, Ho William, Iturritza Miren Urrutia, Eory Lel, Malysz Kamila, Sobhiafshar Ulduz, Archibald Alan L, Macqueen Daniel J, Shih Barbara, Garrick David, Vernimmen Douglas

CAR-T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment

与复发时或接受达雷妥尤单抗治疗后产生的CAR-T细胞相比,从多发性骨髓瘤患者确诊时获得的CAR-T细胞具有更强的细胞毒性功能。

Abecassis, Audrey; Roders, Nathalie; Fayon, Maxime; Choisy, Caroline; Nelson, Elisabeth; Harel, Stephanie; Royer, Bruno; Villesuzanne, Camille; Talbot, Alexis; Garrick, David; Goodhardt, Michele; Fermand, Jean-Paul; Burbridge, Mike; Arnulf, Bertrand; Bories, Jean-Christophe

Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation

造血干细胞中组蛋白甲基转移酶SUV39H1的年龄相关性下降会扰乱异染色质和B淋巴细胞分化

Djeghloul, Dounia; Kuranda, Klaudia; Kuzniak, Isabelle; Barbieri, Daniela; Naguibneva, Irina; Choisy, Caroline; Bories, Jean-Christophe; Dosquet, Christine; Pla, Marika; Vanneaux, Valérie; Socié, Gérard; Porteu, Françoise; Garrick, David; Goodhardt, Michele

The role of the polycomb complex in silencing alpha-globin gene expression in nonerythroid cells

多梳蛋白复合物在非红细胞中抑制α-珠蛋白基因表达的作用

Garrick, David; De Gobbi, Marco; Samara, Vasiliki; Rugless, Michelle; Holland, Michelle; Ayyub, Helena; Lower, Karen; Sloane-Stanley, Jackie; Gray, Nicki; Koch, Christoph; Dunham, Ian; Higgs, Douglas R

Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse model

利用小鼠模型确定X连锁智力低下中X染色体失活偏倚的原因

Muers, Mary R; Sharpe, Jacqueline A; Garrick, David; Sloane-Stanley, Jacqueline; Nolan, Patrick M; Hacker, Terry; Wood, William G; Higgs, Douglas R; Gibbons, Richard J

The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis

染色质重塑蛋白ATRX对于皮层发育过程中神经元的存活至关重要。

Bérubé, Nathalie G; Mangelsdorf, Marie; Jagla, Magdalena; Vanderluit, Jackie; Garrick, David; Gibbons, Richard J; Higgs, Douglas R; Slack, Ruth S; Picketts, David J