Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs
通过链间半胱氨酸交联获得的抗体-药物偶联物 (ADC) 比传统的异质性 ADC 具有更好的均质性和其他药理特性
期刊:Molecular Pharmaceutics
影响因子:3.2
doi:10.1021/acs.molpharmaceut.5b00432
Christopher R Behrens, Edward H Ha, Lawrence L Chinn, Simeon Bowers, Gary Probst, Maureen Fitch-Bruhns, Jorge Monteon, Amanda Valdiosera, Abel Bermudez, Sindy Liao-Chan, Tiffany Wong, Jonathan Melnick, Jan-Willem Theunissen, Mark R Flory, Derrick Houser, Kristy Venstrom, Zoia Levashova, Paul Sauer,
