日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice

基质金属蛋白酶-2和MMP-9在小鼠实验性肺纤维化中的作用

Tina Bormann, Regina Maus, Jennifer Stolper, Meritxell Tort Tarrés, Christina Brandenberger, Dirk Wedekind, Danny Jonigk, Tobias Welte, Jack Gauldie, Martin Kolb, Ulrich A Maus

FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis

FPR-1 是中性粒细胞募集的重要调节剂,也是肺纤维化的组织特异性驱动因素

Jack Leslie, Ben Jm Millar, Alicia Del Carpio Pons, Rachel A Burgoyne, Joseph D Frost, Ben S Barksby, Saimir Luli, Jon Scott, A John Simpson, Jack Gauldie, Lynne A Murray, Donna K Finch, Alan M Carruthers, John Ferguson, Matthew A Sleeman, David Rider, Rachel Howarth, Christopher Fox, Fiona Oakley, 

Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension

马西替坦减缓 TGF-β1 诱发的肺纤维化和肺动脉高压的进展

Pierre-Simon Bellaye, Toyoshi Yanagihara, Elise Granton, Seidai Sato, Chiko Shimbori, Chandak Upagupta, Jewel Imani, Nathan Hambly, Kjetil Ask, Jack Gauldie, Marc Iglarz, Martin Kolb

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

纳米尺度下胶原蛋白结构-功能的失调会破坏机械稳态并介导肺纤维化

Jones, Mark G; Andriotis, Orestis G; Roberts, James Jw; Lunn, Kerry; Tear, Victoria J; Cao, Lucy; Ask, Kjetil; Smart, David E; Bonfanti, Alessandra; Johnson, Peter; Alzetani, Aiman; Conforti, Franco; Doherty, Regan; Lai, Chester Y; Johnson, Benjamin; Bourdakos, Konstantinos N; Fletcher, Sophie V; Marshall, Ben G; Jogai, Sanjay; Brereton, Christopher J; Chee, Serena J; Ottensmeier, Christian H; Sime, Patricia; Gauldie, Jack; Kolb, Martin; Mahajan, Sumeet; Fabre, Aurelie; Bhaskar, Atul; Jarolimek, Wolfgang; Richeldi, Luca; O'Reilly, Katherine Ma; Monk, Phillip D; Thurner, Philipp J; Davies, Donna E

Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo

TGF-β1 过度表达期间的表面活性物质功能障碍先于体内促纤维化肺重塑

Elena Lopez-Rodriguez, Caroline Boden, Mercedes Echaide, Jesus Perez-Gil, Martin Kolb, Jack Gauldie, Ulrich A Maus, Matthias Ochs, Lars Knudsen

Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

TGFβ诱导ITGB6基因转录扩增可能促进肺纤维化

Amanda L Tatler, Amanda T Goodwin, Olumide Gbolahan, Gauri Saini, Joanne Porte, Alison E John, Rachel L Clifford, Shelia M Violette, Paul H Weinreb, Helen Parfrey, Paul J Wolters, Jack Gauldie, Martin Kolb, Gisli Jenkins

A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells

一种新型促纤维化机制,由TGFβ刺激的胶原脯氨酰羟化酶在纤维化肺间充质细胞中的表达介导。

Yongfeng Luo ,Wei Xu ,Hui Chen ,David Warburton ,Rachel Dong ,Bangping Qian ,Moisés Selman ,Jack Gauldie ,Martin Kolb ,Wei Shi

Matrix metalloproteinase-19 promotes metastatic behavior in vitro and is associated with increased mortality in non-small cell lung cancer

基质金属蛋白酶-19在体外促进转移行为,并与非小细胞肺癌死亡率增加相关。

Yu, Guoying; Herazo-Maya, Jose D; Nukui, Tomoko; Romkes, Marjorie; Parwani, Anil; Juan-Guardela, Brenda M; Robertson, Jennifer; Gauldie, Jack; Siegfried, Jill M; Kaminski, Naftali; Kass, Daniel J

Type 1 interferon gene transfer enhances host defense against pulmonary Streptococcus pneumoniae infection via activating innate leukocytes

I型干扰素基因转移通过激活固有白细胞增强宿主对肺部肺炎链球菌感染的防御能力

Damjanovic, Daniela; Khera, Amandeep; Medina, Maria Fe; Ennis, Jane; Turner, Jeffrey D; Gauldie, Jack; Xing, Zhou

Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer

MMP-9 诱导的炎症促进实验性乳腺癌肿瘤消退

Karin Söderlund Leifler, Susanne Svensson, Annelie Abrahamsson, Christina Bendrik, Jennifer Robertson, Jack Gauldie, Anna-Karin Olsson, Charlotta Dabrosin