日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Sensitive Whole Blood Assay Detects Antigen-Stimulated Cytokine Release From CD4+ T Cells and Facilitates Immunomonitoring in a Phase 2 Clinical Trial of Nexvax2 in Coeliac Disease

灵敏的全血检测可检测 CD4+ T 细胞中抗原刺激的细胞因子释放,并有助于在 Nexvax2 治疗乳糜泻的 2 期临床试验中进行免疫监测

Melinda Y Hardy, Gautam Goel, Amy K Russell, Swee Lin G Chen Yi Mei, Gregor J E Brown, Suyue Wang, Evan Szymczak, Ruan Zhang, Kaela E Goldstein, Kristin M Neff, Leslie J Williams, Kenneth E Truitt, John L Dzuris, Jason A Tye-Din, Robert P Anderson

Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease

乳糜泻患者麸质激发试验后细胞因子释放和胃肠道症状

Gautam Goel ,Jason A Tye-Din ,Shuo-Wang Qiao ,Amy K Russell ,Toufic Mayassi ,Cezary Ciszewski ,Vikas K Sarna ,Suyue Wang ,Kaela E Goldstein ,John L Dzuris ,Leslie J Williams ,Ramnik J Xavier ,Knut E A Lundin ,Bana Jabri ,Ludvig M Sollid ,Robert P Anderson

New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling

半乳糖凝集素-3 在高亲和力 IgE 受体信号转导中的新调节作用

Monika Bambouskova, Iva Polakovicova, Ivana Halova, Gautam Goel, Lubica Draberova, Viktor Bugajev, Aivi Doan, Pavol Utekal, Agnes Gardet, Ramnik J Xavier, Petr Draber

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages

丙酮酸激酶 M2 调节 Hif-1α 活性和 IL-1β 诱导,是 LPS 激活巨噬细胞中瓦伯格效应的关键决定因素

Eva M Palsson-McDermott, Anne M Curtis, Gautam Goel, Mario A R Lauterbach, Frederick J Sheedy, Laura E Gleeson, Mirjam W M van den Bosch, Susan R Quinn, Raquel Domingo-Fernandez, Daniel G W Johnston, Jian-Kang Jiang, William J Israelsen, Joseph Keane, Craig Thomas, Clary Clish, Matthew Vander Heiden

Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst

功能基因组学识别控制吞噬细胞氧化爆发的负调控节点

Daniel B Graham, Christine E Becker, Aivi Doan, Gautam Goel, Eduardo J Villablanca, Dan Knights, Amanda Mok, Aylwin C Y Ng, John G Doench, David E Root, Clary B Clish, Ramnik J Xavier

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells

激酶 DYRK1A 相互调节 Th17 和调节性 T 细胞的分化

Bernard Khor, John D Gagnon, Gautam Goel, Marly I Roche, Kara L Conway, Khoa Tran, Leslie N Aldrich, Thomas B Sundberg, Alison M Paterson, Scott Mordecai, David Dombkowski, Melanie Schirmer, Pauline H Tan, Atul K Bhan, Rahul Roychoudhuri, Nicholas P Restifo, John J O'Shea, Benjamin D Medoff, Alykhan

Multivariate inference of pathway activity in host immunity and response to therapeutics

宿主免疫和治疗反应中通路活性的多变量推断

Gautam Goel, Kara L Conway, Martin Jaeger, Mihai G Netea, Ramnik J Xavier

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma

Atg5-Atg12/Atg16L1自噬蛋白复合物在干扰素γ抗病毒活性中的非降解作用

Seungmin Hwang ,Nicole S Maloney, Monique W Bruinsma, Gautam Goel, Erning Duan, Lei Zhang, Bimmi Shrestha, Michael S Diamond, Adish Dani, Stanislav V Sosnovtsev, Kim Y Green, Carlos Lopez-Otin, Ramnik J Xavier, Larissa B Thackray, Herbert W Virgin