日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy

IL-9 作为一种天然正交细胞因子,具有最佳的 JAK/STAT 信号通路活性,可用于工程化 T 细胞治疗。

Hua Jiang ,Sam Limsuwannarot ,Kayla R Kulhanek ,Aastha Pal ,Ossama Labiad ,Lea W Rysavy ,Ada Wong ,Leon Su ,Sarah Cavender ,Johnathon Soro ,Stefano Testa ,Heather Ogana ,Deepa Waghray ,Pingdong Tao ,Kevin M Jude ,Christopher S Seet ,Gay M Crooks ,Everett J Moding ,K Christopher Garcia ,Anusha Kalbasi

Increased expression of Toll-like receptors and associated alarmins in temporal arteries of patients with giant cell arteritis

巨细胞动脉炎患者颞动脉中 Toll 样受体及相关报警素表达增加

Seidlberger, S; Schirmer, M; Wietzorrek, G; Jiménez-Heffernan, J A; Pardines, M; de Las Fuentes Monreal, M; González-Gay, M A; Castañeda, S; Santos-Sierra, S

Deciphering Pain Experience in Adult Patients With Sickle Cell Disease: A Network Analysis of Pain-Related Factors in a Single French Sickle Cell Centre

解读镰状细胞病成年患者的疼痛体验:法国某镰状细胞病中心疼痛相关因素的网络分析

Oudin Doglioni, D; Couette, M; Forté, S; Galacteros, F; Gay, M-C

IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy

IL-9 作为一种天然正交细胞因子,具有最佳的 JAK/STAT 信号通路活性,可用于工程化 T 细胞治疗。

Jiang, Hua; Limsuwannarot, Sam; Kulhanek, Kayla R; Pal, Aastha; Rysavy, Lea W; Su, Leon; Labiad, Ossama; Testa, Stefano; Ogana, Heather; Waghray, Deepa; Tao, Pingdong; Jude, Kevin M; Seet, Christopher S; Crooks, Gay M; Moding, Everett J; Garcia, K Christopher; Kalbasi, Anusha

MYCT1 controls environmental sensing in human haematopoietic stem cells

MYCT1 控制人类造血干细胞的环境感知

Júlia Aguadé-Gorgorió ,Yasaman Jami-Alahmadi ,Vincenzo Calvanese ,Maya Kardouh ,Iman Fares ,Haley Johnson ,Valerie Rezek ,Feiyang Ma ,Mattias Magnusson ,Yanling Wang ,Juliana E Shin ,Karina J Nance ,Helen S Goodridge ,Simone Liebscher ,Katja Schenke-Layland ,Gay M Crooks ,James A Wohlschlegel ,Hanna K A Mikkola

Generation of antigen-specific mature T cells from RAG1-/-RAG2-/-B2M-/- stem cells by engineering their microenvironment

通过改造微环境,从 RAG1-/-RAG2-/-B2M-/- 干细胞生成抗原特异性成熟 T 细胞

Patrick C Chang ,Xuegang Yuan # ,Alexandre Zampieri # ,Chloe Towns ,Sang Pil Yoo ,Claire Engstrom ,Steven Tsai ,Christopher R Robles ,Yuhua Zhu ,Shawn Lopez ,Amelie Montel-Hagen ,Christopher S Seet ,Gay M Crooks

Lentiviral vectors for precise expression to treat X-linked lymphoproliferative disease

慢病毒载体精准表达治疗X连锁淋巴细胞增生性疾病

Paul G Ayoub, Julia Gensheimer, Lindsay Lathrop, Colin Juett, Jason Quintos, Kevin Tam, Jack Reid, Feiyang Ma, Curtis Tam, Grace E McAuley, Devin Brown, Xiaomeng Wu, Ruixue Zhang, Kathryn Bradford, Roger P Hollis, Gay M Crooks, Donald B Kohn

Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing

通过腺嘌呤碱基编辑,CD3δ重症联合免疫缺陷中的人类T细胞生成得以恢复。

Grace E McAuley ,Gloria Yiu ,Patrick C Chang ,Gregory A Newby ,Beatriz Campo-Fernandez ,Sorel T Fitz-Gibbon ,Xiaomeng Wu ,Sung-Hae L Kang ,Amber Garibay ,Jeffrey Butler ,Valentina Christian ,Ryan L Wong ,Kelcee A Everette ,Anthony Azzun ,Hila Gelfer ,Christopher S Seet ,Aru Narendran ,Luis Murguia-Favela ,Zulema Romero ,Nicola Wright ,David R Liu ,Gay M Crooks ,Donald B Kohn

IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing

IRIS:发现源于前体mRNA选择性剪接的癌症免疫治疗靶点

Pan, Yang; Phillips, John W; Zhang, Beatrice D; Noguchi, Miyako; Kutschera, Eric; McLaughlin, Jami; Nesterenko, Pavlo A; Mao, Zhiyuan; Bangayan, Nathanael J; Wang, Robert; Tran, Wendy; Yang, Harry T; Wang, Yuanyuan; Xu, Yang; Obusan, Matthew B; Cheng, Donghui; Lee, Alex H; Kadash-Edmondson, Kathryn E; Champhekar, Ameya; Puig-Saus, Cristina; Ribas, Antoni; Prins, Robert M; Seet, Christopher S; Crooks, Gay M; Witte, Owen N; Xing, Yi

Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells

CAR信号强度决定多能干细胞分化为T细胞还是ILC细胞

Suwen Li ,Chloe S Wang ,Amélie Montel-Hagen ,Ho-Chung Chen ,Shawn Lopez ,Olivia Zhou ,Kristy Dai ,Steven Tsai ,William Satyadi ,Carlos Botero ,Claudia Wong ,David Casero ,Gay M Crooks ,Christopher S Seet