Inhibiting microtubule polymerization with EAPB02303, a prodrug activated by catechol-O-methyl transferase, enhances paclitaxel effect in pancreatic cancer models
EAPB02303是一种由儿茶酚-O-甲基转移酶激活的前药，它能抑制微管聚合，从而增强紫杉醇在胰腺癌模型中的疗效。
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07747-1
Bigot, Kévin; Patinote, Cindy; Garambois, Véronique; Chouchou, Adrien; Gayraud-Paniagua, Stéphanie; Vie, Nadia; Maggipinto, Yann; Smyej, Elias; Robin, Mathilde; Machu, Margot; Bruciamacchie, Marine; Colombo, Pierre-Emmanuel; Bousquet, Corinne; Mathonnet, Muriel; Levy-Augé, Ela; Tosi, Diego; Bonnet, Pierre-Antoine; Gongora, Céline; Deleuze-Masquéfa, Carine; Larbouret, Christel
