日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A dual role for GLI3 signaling in neural crest development

GLI3信号在神经嵴发育中的双重作用

Han, Simon J Y; Adani, Vinit; Farrow, Edward; Parmar, Bhaval; Chang, Ching-Fang; Cochran, Kim; Horne, Ronald R; Ramkissoon, Paige J K; Esteban, Ezekiel; Elliott, Kelsey H; Peterson, Kevin A; Gebelein, Brian; García-Castro, Martín I; Brugmann, Samantha A

An inducible system to study the regulatory functions of GSX2 in human lateral ganglionic eminence-like progenitors

利用诱导系统研究GSX2在人类侧神经节隆起样祖细胞中的调控功能

Farrow, Edward; Rao, Smitha; Han, Simon J Y; Chang, Xuyao; Huynh, Cindy; Brugmann, Samantha A; Lim, Hee-Woong; Tchieu, Jason; Campbell, Kenneth; Gebelein, Brian

The ALX4 dimer structure provides insight into how disease alleles impact function.

ALX4 二聚体结构有助于了解疾病等位基因如何影响功能

Cain Brittany, Yuan Zhenyu, Thoman Evelyn, Kovall Rhett A, Gebelein Brian

Defective Notch1 signaling in endothelial cells drives pathogenesis in a mouse model of Adams-Oliver syndrome

内皮细胞中Notch1信号传导缺陷驱动Adams-Oliver综合征小鼠模型的发病机制

Solano, Alyssa F; Preusse, Kristina; Cain, Brittany; Hotz, Rebecca; Gavini, Parthav; Yuan, Zhenyu; Bowen, Benjamin; Maco, Gabrielle; Neal, Hope; Gagliani, Ellen K; Ahn, Christopher; Lim, Hee-Woong; Southgate, Laura; Kovall, Rhett A; Kopan, Raphael; Gebelein, Brian

Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse brain defects

对一种选择性改变DNA结合的致病性GSX2变体进行建模,揭示了小鼠脑部功能减弱的缺陷。

Laura Tweedie ,Matthew R Riccetti ,Brittany Cain ,Shenyue Qin ,Joseph Salomone ,Jordan A Webb ,Amy Riesenberg ,Lisa A Ehrman ,Ronald R Waclaw ,Rhett A Kovall ,Brian Gebelein ,Kenneth Campbell

A model of transcriptional bursting dynamics based on coupling between chromatin and enhancer states

基于染色质和增强子状态耦合的转录爆发动力学模型

Axelrod, Ofri; Binshtok, Udi; Gebelein, Brian; Garcia, Hernan G; Sprinzak, David

Decoding the mechanisms of cooperative DNA binding by the Paired-like homeodomain family

解码 Paired-like 同源域家族协同 DNA 结合的机制

Cain, Brittany; Wasmund, Connor; Rowan, Fiona C; Gebelein, Brian

Cooperative Gsx2-DNA binding requires DNA bending and a novel Gsx2 homeodomain interface

Gsx2 与 DNA 的协同结合需要 DNA 弯曲和一种新型的 Gsx2 同源域界面。

Webb, Jordan A; Farrow, Edward; Cain, Brittany; Yuan, Zhenyu; Yarawsky, Alexander E; Schoch, Emma; Gagliani, Ellen K; Herr, Andrew B; Gebelein, Brian; Kovall, Rhett A

Homeodomain complex formation and biomolecular condensates in Hox gene regulation

同源域复合物的形成和生物分子凝聚体在Hox基因调控中的作用

Salomone, Joseph; Farrow, Edward; Gebelein, Brian

Prediction of cooperative homeodomain DNA binding sites from high-throughput-SELEX data

利用高通量SELEX数据预测协同同源域DNA结合位点

Cain, Brittany; Webb, Jordan; Yuan, Zhenyu; Cheung, David; Lim, Hee-Woong; Kovall, Rhett A; Weirauch, Matthew T; Gebelein, Brian