Arbutin abrogates cisplatin-induced hepatotoxicity via upregulating Nrf2/HO-1 and suppressing genotoxicity, NF-κB/iNOS/TNF-α and caspase-3/Bax/Bcl2 signaling pathways in rats.
熊果苷通过上调 Nrf2/HO-1 和抑制基因毒性、NF-κB/iNOS/TNF-α 和 caspase-3/Bax/Bcl2 信号通路来消除顺铂引起的肝毒性
期刊:Toxicology Research
影响因子:2.1
doi:10.1093/toxres/tfae075
Okkay Irmak Ferah, Famurewa Ademola, Bayram Cemil, Okkay Ufuk, Mendil Ali Sefa, Sezen Selma, Ayaz Teslime, Gecili Ibrahim, Ozkaraca Mustafa, Senyayla Selcuk, Hacimuftuoglu Ahmet
