日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ileo-colonic delivery of conjugated bile acids improves glucose homeostasis via colonic GLP-1-producing enteroendocrine cells in human obesity and diabetes

回结肠输送结合胆汁酸可通过人类肥胖和糖尿病中结肠产生 GLP-1 的肠内分泌细胞改善葡萄糖稳态

Gerardo Calderon, Alison McRae, Juraj Rievaj, Judith Davis, Inuk Zandvakili, Sara Linker-Nord, Duane Burton, Geoffrey Roberts, Frank Reimann, Bronislava Gedulin, Adrian Vella, Nicholas F LaRusso, Michael Camilleri, Fiona M Gribble, Andres Acosta

Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial

在健康成人和 2 型糖尿病患者中,使用沃利西巴抑制顶端钠依赖性胆汁酸转运蛋白的安全性、耐受性和药效学:一项随机安慰剂对照试验

Tiessen, Renger G; Kennedy, Ciara A; Keller, Bradley T; Levin, Nancy; Acevedo, Lisette; Gedulin, Bronislava; van Vliet, Andre A; Dorenbaum, Alejandro; Palmer, Melissa

A novel long-acting glucose-dependent insulinotropic peptide analogue: enhanced efficacy in normal and diabetic rodents

一种新型长效葡萄糖依赖性促胰岛素肽类似物:在正常和糖尿病啮齿动物中疗效增强

Tatarkiewicz, K; Hargrove, D M; Jodka, C M; Gedulin, B R; Smith, P A; Hoyt, J A; Lwin, A; Collins, L; Mamedova, L; Levy, O E; D'Souza, L; Janssen, S; Srivastava, V; Ghosh, S S; Parkes, D G

Improved glucose control and reduced body weight in rodents with dual mechanism of action peptide hybrids

具有双重作用机制的肽杂合物可改善啮齿动物的血糖控制并降低体重

Trevaskis, James L; Mack, Christine M; Sun, Chengzao; Soares, Christopher J; D'Souza, Lawrence J; Levy, Odile E; Lewis, Diane Y; Jodka, Carolyn M; Tatarkiewicz, Krystyna; Gedulin, Bronislava; Gupta, Swati; Wittmer, Carrie; Hanley, Michael; Forood, Bruce; Parkes, David G; Ghosh, Soumitra S

Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes

抑制顶端钠依赖性胆汁酸转运体作为治疗糖尿病的新方法

Lihong Chen, Xiaozhou Yao, Andrew Young, Judi McNulty, Don Anderson, Yaping Liu, Christopher Nystrom, Dallas Croom, Sean Ross, Jon Collins, Deepak Rajpal, Kimberly Hamlet, Chari Smith, Bronislava Gedulin

Assessment of major and minor groove DNA interactions by the zinc fingers of Xenopus transcription factor IIIA

利用非洲爪蟾转录因子IIIA的锌指评估DNA大沟和小沟的相互作用

McBryant, S J; Gedulin, B; Clemens, K R; Wright, P E; Gottesfeld, J M