日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanisms and regulation of substrate degradation by the 26S proteasome

26S蛋白酶体底物降解的机制和调控

Arkinson, Connor; Dong, Ken C; Gee, Christine L; Martin, Andreas

Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1

降解的 26S 蛋白酶体的结构图谱揭示了 TXNL1 的构象特异性结合

Arkinson, Connor; Gee, Christine L; Zhang, Zeyuan; Dong, Ken C; Martin, Andreas

NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome.

NUB1 捕获未折叠的 FAT10,使其通过 26S 蛋白酶体进行不依赖泛素的降解

Arkinson Connor, Dong Ken C, Gee Christine L, Costello Shawn M, Soe Aimee Chi, Hura Greg L, Marqusee Susan, Martin Andreas

Reactive oxygen species control protein degradation at the mitochondrial import gate.

活性氧控制线粒体输入门处的蛋白质降解

McMinimy Rachael, Manford Andrew G, Gee Christine L, Chandrasekhar Srividya, Mousa Gergey Alzaem, Chuang Joelle, Phu Lilian, Shih Karen Y, Rose Christopher M, Kuriyan John, Bingol Baris, Rapé Michael

Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1

底物降解型人类26S蛋白酶体中AAA+ ATPase马达状态的结构图谱揭示了TXNL1的构象特异性结合

Arkinson, Connor; Gee, Christine L; Zhang, Zeyuan; Dong, Ken C; Martin, Andreas

Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase

大豆脂氧合酶中激活氢隧道效应的远端蛋白质运动的时间和空间分辨率

Zaragoza, Jan Paulo T; Offenbacher, Adam R; Hu, Shenshen; Gee, Christine L; Firestein, Zachary M; Minnetian, Natalie; Deng, Zhenyu; Fan, Flora; Iavarone, Anthony T; Klinman, Judith P

GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

GHB类似物通过与CaMKIIα枢纽结构域的特异性相互作用发挥神经保护作用。

Leurs, Ulrike; Klein, Anders B; McSpadden, Ethan D; Griem-Krey, Nane; Solbak, Sara M Ø; Houlton, Josh; Villumsen, Inge S; Vogensen, Stine B; Hamborg, Louise; Gauger, Stine J; Palmelund, Line B; Larsen, Anne Sofie G; Shehata, Mohamed A; Kelstrup, Christian D; Olsen, Jesper V; Bach, Anders; Burnie, Robert O; Kerr, D Steven; Gowing, Emma K; Teurlings, Selina M W; Chi, Chris C; Gee, Christine L; Frølund, Bente; Kornum, Birgitte R; van Woerden, Geeske M; Clausen, Rasmus P; Kuriyan, John; Clarkson, Andrew N; Wellendorph, Petrine

Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases

Syk和ZAP-70酪氨酸激酶串联SH2模块动力学的差异

Hobbs, Helen T; Shah, Neel H; Badroos, Jean M; Gee, Christine L; Marqusee, Susan; Kuriyan, John

Exploring the Evolutionary History of Kinetic Stability in the α-Lytic Protease Family

探索α-裂解蛋白酶家族动力学稳定性的进化历史

Nixon, Charlotte F; Lim, Shion A; Sailer, Zachary R; Zheludev, Ivan N; Gee, Christine L; Kelch, Brian A; Harms, Michael J; Marqusee, Susan

Structures of two novel crystal forms of Aspergillus oryzae alpha amylase (taka-amylase)

米曲霉α-淀粉酶(高淀粉酶)两种新型晶体形式的结构

Gee, Christine L; Holton, James M; McPherson, Alexander