日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

利用新型检测方法对实体瘤进行全面的基因组分析,以用于临床诊断中的广泛分析

Froyen, Guy; Volders, Pieter-Jan; Geerdens, Ellen; Berden, Severine; Van der Meulen, Joni; De Cock, Aaron; Vermeire, Stefanie; Van Huysse, Jacques; de Barsy, Marie; Beniuga, Gabriela; de Leng, Wendy W J; Jansen, Anne M L; Demers, Imke; Ozgur, Zeliha; Dubbink, Hendrikus Jan; Speel, Ernst-Jan M; van IJcken, Wilfred F J; Maes, Brigitte

The Dynamics of Nucleotide Variants in the Progression from Low-Intermediate Myeloma Precursor Conditions to Multiple Myeloma: Studying Serial Samples with a Targeted Sequencing Approach

利用靶向测序方法研究从低危-中危骨髓瘤前体状态到多发性骨髓瘤进展过程中核苷酸变异的动态变化

Oben, Bénedith; Cosemans, Charlotte; Geerdens, Ellen; Linsen, Loes; Vanhees, Kimberly; Maes, Brigitte; Theunissen, Koen; Cruys, Bert; Lionetti, Marta; Arijs, Ingrid; Bolli, Niccolò; Froyen, Guy; Rummens, Jean-Luc

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.

Suz12 失活与 JAK3 突变信号传导协同作用,导致 T 细胞急性淋巴细胞白血病的发生

Broux Michael, Prieto Cristina, Demeyer Sofie, Vanden Bempt Marlies, Alberti-Servera Llucia, Lodewijckx Inge, Vandepoel Roel, Mentens Nicole, Gielen Olga, Jacobs Kris, Geerdens Ellen, Vicente Carmen, de Bock Charles E, Cools Jan

Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia

单细胞测序揭示了T细胞急性淋巴细胞白血病中突变的起源和获得顺序

De Bie, Jolien; Demeyer, Sofie; Alberti-Servera, Llucia; Geerdens, Ellen; Segers, Heidi; Broux, Michaël; De Keersmaecker, Kim; Michaux, Lucienne; Vandenberghe, Peter; Voet, Thierry; Boeckx, Nancy; Uyttebroeck, Anne; Cools, Jan

Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene

伴有RNF213、ATIC和TPM3-ALK融合变异的间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤的特征是重排的ALK基因拷贝数增加。

van der Krogt, Jo-Anne; Bempt, Marlies Vanden; Ferreiro, Julio Finalet; Mentens, Nicole; Jacobs, Kris; Pluys, Ursula; Doms, Kathleen; Geerdens, Ellen; Uyttebroeck, Anne; Pierre, Pascal; Michaux, Lucienne; Devos, Timothy; Vandenberghe, Peter; Tousseyn, Thomas; Cools, Jan; Wlodarska, Iwona

Low frequency mutations in ribosomal proteins RPL10 and RPL5 in multiple myeloma

多发性骨髓瘤中核糖体蛋白RPL10和RPL5的低频突变

Hofman, Isabel J F; Patchett, Stephanie; van Duin, Mark; Geerdens, Ellen; Verbeeck, Jelle; Michaux, Lucienne; Delforge, Michel; Sonneveld, Pieter; Johnson, Arlen W; De Keersmaecker, Kim

RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications

RNA测序揭示了难治性/复发性T细胞急性淋巴细胞白血病的遗传学特征。其预后和治疗意义

Gianfelici, Valentina; Chiaretti, Sabina; Demeyer, Sofie; Di Giacomo, Filomena; Messina, Monica; La Starza, Roberta; Peragine, Nadia; Paoloni, Francesca; Geerdens, Ellen; Pierini, Valentina; Elia, Loredana; Mancini, Marco; De Propris, Maria Stefania; Apicella, Valerio; Gaidano, Gianluca; Testi, Anna Maria; Vitale, Antonella; Vignetti, Marco; Mecucci, Cristina; Guarini, Anna; Cools, Jan; Foà, Robin

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia

靶向测序揭示了IL7R-JAK突变与T细胞急性淋巴细胞白血病中表观遗传调节因子之间的关联

Vicente, Carmen; Schwab, Claire; Broux, Michaël; Geerdens, Ellen; Degryse, Sandrine; Demeyer, Sofie; Lahortiga, Idoya; Elliott, Alannah; Chilton, Lucy; La Starza, Roberta; Mecucci, Cristina; Vandenberghe, Peter; Goulden, Nicholas; Vora, Ajay; Moorman, Anthony V; Soulier, Jean; Harrison, Christine J; Clappier, Emmanuelle; Cools, Jan

Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia

T细胞急性淋巴细胞白血病中的Hedgehog通路突变

Dagklis, Antonis; Pauwels, Daphnie; Lahortiga, Idoya; Geerdens, Ellen; Bittoun, Emilie; Cauwelier, Barbara; Tousseyn, Thomas; Uyttebroeck, Anne; Maertens, Johan; Verhoef, Gregor; Vandenberghe, Peter; Cools, Jan

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

T细胞急性淋巴细胞白血病中Notch驱动的长链非编码RNA库

Durinck, Kaat; Wallaert, Annelynn; Van de Walle, Inge; Van Loocke, Wouter; Volders, Pieter-Jan; Vanhauwaert, Suzanne; Geerdens, Ellen; Benoit, Yves; Van Roy, Nadine; Poppe, Bruce; Soulier, Jean; Cools, Jan; Mestdagh, Pieter; Vandesompele, Jo; Rondou, Pieter; Van Vlierberghe, Pieter; Taghon, Tom; Speleman, Frank