Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment
人类 E46K 突变 α-突触核蛋白在 BAC 转基因大鼠中的表达复制了早期帕金森病的特征并增强了对线粒体损伤的脆弱性
期刊:Experimental Neurology
影响因子:4.6
doi:10.1016/j.expneurol.2012.11.007
Jason R Cannon, Kindiya D Geghman, Victor Tapias, Thomas Sew, Michelle K Dail, Chenjian Li, J Timothy Greenamyre