日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Serum drug levels and JCV assay discrepancies after switching from originator to biosimilar natalizumab

从原研药换用生物类似药那他珠单抗后，血清药物浓度和JCV检测结果出现差异

期刊:BMJ Neurology Open
影响因子:2.4
doi:10.1136/bmjno-2025-001477
Høgestøl, Einar August; Brustad, Åge Winje; Celius, Elisabeth Gulowsen; Meling, Martine; Berg-Hansen, Pål; Kro, Grete Birkeland; König, Marton; Schanke, Ylva; Halvorsen, Bente; Warren, David J; Gehin, Johanna E; Bolstad, Nils; Nygaard, Gro Owren
发表日期：2026
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Cost-effectiveness of proactive therapeutic drug monitoring of maintenance infliximab treatment in patients with immune-mediated inflammatory diseases: results from a randomised controlled trial

对免疫介导炎症性疾病患者进行英夫利昔单抗维持治疗的主动治疗药物监测的成本效益：一项随机对照试验的结果

期刊:RMD Open
影响因子:
doi:10.1136/rmdopen-2025-006329
Holly, Teresa; Kirkesaether Brun, Marthe; Jørgensen, Kristin Kaasen; Goll, Guro Løvik; Sexton, Joseph; Gehin, Johanna Elin; Kvien, Tore K; Jahnsen, Jørgen; Provan, Sella A; Bolstad, Nils; Aas, Eline; Haavardsholm, Espen A; Kristiansen, Ivar S; Syversen, Silje Watterdal; Hagen, Gunhild
炎症/感染
炎症
免疫/内分泌
发表日期：2026
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Newly-diagnosed rheumatoid arthritis patients have elevated levels of plasma extracellular vesicles with protein cargo altered towards inflammatory processes.

新确诊的类风湿性关节炎患者血浆细胞外囊泡水平升高，其蛋白质载荷发生改变，趋向于炎症过程

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-96325-8
Rydland Anne, Heinicke Fatima, Nyman Tuula A, Trøseid Anne-Marie Siebke, Flåm Siri T, Stensland Maria, Gehin Johanna, Eikeland Joakim, Øvstebø Reidun, Mjaavatten Maria Dahl, Lie Benedicte A
细胞生物学
关节炎
囊泡
炎症
发表日期：2025
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Therapeutic serum level for adalimumab in rheumatoid arthritis: explorative analyses of data from a randomised phase III trial

阿达木单抗治疗类风湿性关节炎的血清治疗浓度：一项随机 III 期试验数据的探索性分析

期刊:RMD Open
影响因子:4.7
doi:10.1136/rmdopen-2024-004888
Gehin, Johanna Elin; Klaasen, Rolf Anton; Klami Kristianslund, Eirik; Jyssum, Ingrid; Sexton, Joseph; Warren, David John; Aletaha, Daniel; Haavardsholm, Espen Andre; Syversen, Silje Watterdal; Goll, Guro Løvik; Bolstad, Nils
关节炎
发表日期：2024
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Adalimumab serum levels and anti-drug antibodies: associations to treatment response and drug survival in inflammatory joint diseases

阿达木单抗血清水平和抗药抗体：与炎症性关节疾病的治疗反应和药物生存率的相关性

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/kead525
Jyssum, Ingrid; Gehin, Johanna E; Sexton, Joseph; Kristianslund, Eirik Klami; Hu, Yi; Warren, David John; Kvien, Tore K; Haavardsholm, Espen A; Syversen, Silje Watterdal; Bolstad, Nils; Goll, Guro Løvik
炎症
炎症/感染
发表日期：2024
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Influence of rheumatoid factor levels and TNF inhibitor structure on secondary nonresponse in rheumatoid arthritis patients

类风湿因子水平和TNF抑制剂结构对类风湿关节炎患者继发性无反应的影响

期刊:Frontiers in Medicine
影响因子:3
doi:10.3389/fmed.2024.1461396
Plasencia-Rodríguez, Chamaida; Martínez-Feito, Ana; Novella-Navarro, Marta; Pérez De Diego, Rebeca; Bonilla, Gema; Gehin, Johanna Elin; Villalba-Yllán, Alejandro; Nuño, Laura; Pascual-Salcedo, Dora; Nozal, Pilar; Almirón, Mariana Díaz; Balsa, Alejandro
关节炎
发表日期：2024
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Risk factors for anti-drug antibody formation to infliximab: Secondary analyses of a randomised controlled trial

英夫利昔单抗抗药抗体形成的风险因素：一项随机对照试验的二次分析

期刊:Journal of Internal Medicine
影响因子:9.2
doi:10.1111/joim.13495
Brun, Marthe Kirkesaether; Goll, Guro Løvik; Jørgensen, Kristin Kaasen; Sexton, Joseph; Gehin, Johanna Elin; Sandanger, Øystein; Olsen, Inge Christoffer; Klaasen, Rolf Anton; Warren, David John; Mørk, Cato; Kvien, Tore K; Jahnsen, Jørgen; Bolstad, Nils; Haavardsholm, Espen A; Syversen, Silje Watterdal
发表日期：2022
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Assessing Immunogenicity of Biologic Drugs in Inflammatory Joint Diseases: Progress Towards Personalized Medicine

评估生物制剂在炎症性关节疾病中的免疫原性：迈向个性化医疗的进展

期刊:BioDrugs
影响因子:6.9
doi:10.1007/s40259-022-00559-1
Gehin, Johanna Elin; Goll, Guro Løvik; Brun, Marthe Kirkesæther; Jani, Meghna; Bolstad, Nils; Syversen, Silje Watterdal
炎症/感染
炎症
免疫/内分泌
发表日期：2022
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Therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal disease: a systematic literature review informing EULAR points to consider

炎症性风湿病和肌肉骨骼疾病中生物制药的治疗药物监测：系统性文献综述及EULAR需考虑的要点

期刊:RMD Open
影响因子:4.7
doi:10.1136/rmdopen-2022-002216
Krieckaert, Charlotte; Hernández-Breijo, Borja; Gehin, Johanna Elin; le Mélédo, Guillaume; Balsa, Alejandro; Jani, Meghna; Mulleman, Denis; Navarro-Compan, Victoria; Wolbink, Gertjan; Isaac, John; van Tubergen, Astrid
炎症/感染
炎症
发表日期：2022
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Serum etanercept concentrations in relation to disease activity and treatment response assessed by ultrasound, biomarkers and clinical disease activity scores: results from a prospective observational study of patients with rheumatoid arthritis

血清依那西普浓度与疾病活动度和治疗反应的关系（通过超声、生物标志物和临床疾病活动度评分评估）：一项针对类风湿关节炎患者的前瞻性观察研究结果

期刊:RMD Open
影响因子:4.7
doi:10.1136/rmdopen-2021-001985
Gehin, Johanna Elin; Syversen, Silje Watterdal; Warren, David John; Goll, Guro Løvik; Sexton, Joseph; Bolstad, Nils; Hammer, Hilde Berner
关节炎
发表日期：2021
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