日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Filamin C dimerisation is regulated by HSPB7.

丝状蛋白C二聚化受HSPB7调控

Wang Zihao, Cao Guodong, Collier Miranda P, Qiu Xingyu, Broadway-Stringer Sophie, Šaman Dominik, Ng Jediael Z Y, Sen Navoneel, Azad Amar J, Hooper Charlotte, Zimmermann Johannes, McDonough Michael A, Brem Jürgen, Rabe Patrick, Song Haigang, Alderson T Reid, Schofield Christopher J, Bolla Jani R, Djinovic-Carugo Kristina, Fürst Dieter O, Warscheid Bettina, Degiacomi Matteo T, Allison Timothy M, Hochberg Georg K A, Robinson Carol V, Gehmlich Katja, Benesch Justin L P

Mechanosensitive biochemical imprinting of the talin interaction with DLC1 regulates RhoA activity and cardiomyocyte remodeling.

肌动蛋白与 DLC1 相互作用的机械敏感性生化印记调节 RhoA 活性和心肌细胞重塑

Marhuenda Emilie, Xanthis Ioannis, Smith Poppy O, Prakash Aishwarya, Kallem Till, Pandey Pragati, Wilson Darren Graham Samuel, Azad Amar, Richter Megan, Pavlovic Davor, Gehmlich Katja, Faggian Giuseppe, Swiatlowska Pamela, Ehler Elisabeth, Levitt James, Poland Simon P, Ameer-Beg Simon, Goult Benjamin T, Iskratsch Thomas

Early Atrial Remodeling Drives Arrhythmia in Fabry Disease.

法布里病中,早期心房重构是导致心律失常的主要原因

Roy Ashwin, O'Shea Christopher, Dasí Albert, Patel Leena, Cumberland Max J, Nieves Daniel, Canagarajah Hansel S, Thompson Sophie, Azad Amar, Price Anna M, Hall Caitlin, Alvior Amor Mia B, Rath Phalguni, Davies Ben, Rodriguez Blanca, Holmes Andrew P, Pavlovic Davor, Townend Jonathan N, Geberhiwot Tarekegn, Gehmlich Katja, Steeds Richard P

HCM-Associated MuRF1 Variants Compromise Ubiquitylation and Are Predicted to Alter Protein Structure.

HCM 相关 MuRF1 变体损害泛素化,预计会改变蛋白质结构

Chunthorng-Orn Jitpisute, Noureddine Maya, Dawson Peter W J, Lord Samuel O, Ng Jimi, Boyton Luke, Gehmlich Katja, Mohammed Fiyaz, Lai Yu-Chiang

Substrate stiffness-dependent metabolic reprogramming of iPSC-derived cardiomyocytes on physiological PDMS polymers.

基质刚度依赖性代谢重编程诱导多能干细胞衍生的心肌细胞在生理性PDMS聚合物上的代谢重编程

Patel Leena, Marzullo Bryan P, Barlow Jonathan, Rana Himani, Azad Amar J, Thomas Patricia, Tennant Daniel A, Gehmlich Katja

Fabry Disease: Insights into Pathophysiology and Novel Therapeutic Strategies

法布里病:病理生理学见解及新型治疗策略

Thompson, Sophie Elizabeth; Roy, Ashwin; Geberhiwot, Tarekegn; Gehmlich, Katja; Steeds, Richard Paul

An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten

mavacamten 可部分挽救导致常染色体显性肥厚型心肌病的 ALPK3 截短变异体。

Leinhos, Lisa; Robinson, Paul; Poloni, Giulia; Broadway-Stringer, Sophie; Beglov, Julia; Lokman, Adam B; Douglas, Gillian; Nuthay, Sajjad; Fonseka, Oveena; Schmid, Manuel; Singer, Evie; Hooper, Charlotte; Thomson, Kate; Bagnall, Richard D; Ingles, Jodie; Semsarian, Christopher; Ormondroyd, Elizabeth; Toepfer, Christopher N; Davies, Benjamin; Redwood, Charles; Watkins, Hugh; Gehmlich, Katja

Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease

α-辅肌动蛋白亚型的结构和功能及其在心血管疾病中的作用

Noureddine, Maya; Mikolajek, Halina; Morgan, Neil V; Denning, Chris; Loughna, Siobhan; Gehmlich, Katja; Mohammed, Fiyaz

Atrial electrical alterations with intact cardiac structure and contractile function in a mouse model of an HCM-linked ACTN2 variant.

在 HCM 相关 ACTN2 变异小鼠模型中,心房电活动改变,但心脏结构和收缩功能完整

Noureddine Maya, Broadway-Stringer Sophie, O'Shea Christopher, Jones Bethany A I, Hayes Abbie, Denning Chris, Loughna Siobhan, Mohammed Fiyaz, Pavlovic Davor, Gehmlich Katja

Phenoage and longitudinal changes on transthoracic echocardiography in Alström syndrome: a disease of accelerated ageing?

Alström综合征的表型年龄和经胸超声心动图纵向变化:一种加速衰老的疾病?

Patel, Leena; Roy, Ashwin; Alvior, Amor Mia B; Yuan, Mengshi; Baig, Shanat; Bunting, Karina V; Hodson, James; Gehmlich, Katja; Lord, Janet M; Geberhiwot, Tarekegn; Steeds, Richard P