日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Composite SMG5-SMG6 PIN domain formation is essential for NMD

SMG5-SMG6复合PIN结构域的形成对于NMD至关重要。

Kurscheidt, Katharina; Theunissen, Sophie; Pasquali, Natalia; Becker, Kerstin; Boehm, Volker; Conti, Elena; Gehring, Niels H

SMG1:SMG8:SMG9-complex integrity supports efficient execution of nonsense-mediated mRNA decay

SMG1:SMG8:SMG9复合物的完整性支持无义介导的mRNA降解的高效执行

Kueckelmann, Sabrina; Theunissen, Sophie; Meyer Zu Altenschildesche, Fenja; von Ondarza, Leonie; Lackmann, Jan-Wilm; Franitza, Marek; Becker, Kerstin; Boehm, Volker; Gehring, Niels H

Modulation of UPF1 catalytic activity upon interaction of SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense mediated-mRNA decay.

SARS-CoV-2 核衣壳蛋白与参与无义介导 mRNA 衰变的因子相互作用,从而调节 UPF1 催化活性

Mallick Megha, Boehm Volker, Xue Guangpu, Blackstone Mark, Gehring Niels H, Chakrabarti Sutapa

A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis

线粒体导入途径分为两步,将二硫键传递与基质复合物 I 的生物合成相偶联。

Peker, Esra; Weiss, Konstantin; Song, Jiyao; Zarges, Christine; Gerlich, Sarah; Boehm, Volker; Trifunovic, Aleksandra; Langer, Thomas; Gehring, Niels H; Becker, Thomas; Riemer, Jan

Mechanism, factors, and physiological role of nonsense-mediated mRNA decay

无义介导的mRNA衰变的机制、影响因素和生理作用

Fatscher, Tobias; Boehm, Volker; Gehring, Niels H

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

无义介导衰变因子UPF1和UPF2之间存在不寻常的双向相互作用模式

Clerici, Marcello; Mourão, André; Gutsche, Irina; Gehring, Niels H; Hentze, Matthias W; Kulozik, Andreas; Kadlec, Jan; Sattler, Michael; Cusack, Stephen

The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay

剪接体介导的外显子连接复合物组装的层级结构解释了哺乳动物无义介导的mRNA衰变的关键特征

Gehring, Niels H; Lamprinaki, Styliani; Hentze, Matthias W; Kulozik, Andreas E

Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII

天然产物帕特胺A通过真核起始因子4AIII抑制无义介导的mRNA降解

Dang, Yongjun; Low, Woon-Kai; Xu, Jing; Gehring, Niels H; Dietz, Harry C; Romo, Daniel; Liu, Jun O

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

UPF1、eRFs、PABP 和外显子连接复合物之间的相互作用提示了一种哺乳动物 NMD 通路的整合模型。

Ivanov, Pavel V; Gehring, Niels H; Kunz, Joachim B; Hentze, Matthias W; Kulozik, Andreas E

Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals

剪接因子通过非经典3'末端形成信号处的USE刺激多聚腺苷酸化

Danckwardt, Sven; Kaufmann, Isabelle; Gentzel, Marc; Foerstner, Konrad U; Gantzert, Anne-Susan; Gehring, Niels H; Neu-Yilik, Gabriele; Bork, Peer; Keller, Walter; Wilm, Matthias; Hentze, Matthias W; Kulozik, Andreas E