日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Physiologically Based Pharmacokinetic Model of CYP2D6 Associated Interaction Between Venlafaxine and Strong Inhibitor Bupropion-The Influence of Age-Relevant Changes and Inhibitory Dose to Classify Therapeutical Success and Harm

基于生理的CYP2D6相关药物相互作用的药代动力学模型:文拉法辛与强效抑制剂安非他酮的相互作用——年龄相关变化和抑制剂量对治疗成功与危害的影响

Luecht, Ulrich Ruben; Scholz, Wolfgang; Geiben, Ann-Kathrin; Haen, Ekkehard; Hempel, Georg

In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes

淋巴靶向免疫脂质体包裹的肝素活化丝氨酸蛋白酶抑制剂抗凝血酶 III 的体内抗 HIV 活性

Mohammed Asmal, James B Whitney, Corinne Luedemann, Angela Carville, Robert Steen, Norman L Letvin, Ralf Geiben-Lynn

Modulation of plasmid DNA vaccine antigen clearance by caspase 12 RNA interference potentiates vaccination

通过 caspase 12 RNA 干扰调节质粒 DNA 疫苗抗原清除可增强疫苗接种效果

Geiben-Lynn, Ralf; Frimpong-Boateng, Kwesi; Letvin, Norman L

Regulatory T cells suppress natural killer cells during plasmid DNA vaccination in mice, blunting the CD8+ T cell immune response by the cytokine TGFbeta

在小鼠质粒DNA疫苗接种过程中,调节性T细胞抑制自然杀伤细胞,并通过细胞因子TGFβ减弱CD8+ T细胞的免疫反应。

Frimpong-Boateng, Kwesi; van Rooijen, Nico; Geiben-Lynn, Ralf

CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses

CD4+ T 淋巴细胞介导体内质粒 DNA 疫苗抗原表达的清除,并增强 CD8+ T 细胞的免疫应答。

Geiben-Lynn, Ralf; Greenland, John R; Frimpong-Boateng, Kwesi; van Rooijen, Nico; Hovav, Avi-Hai; Letvin, Norman L

Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses

重组5型腺病毒、痘苗病毒、改良型安卡拉痘苗病毒和DNA抗原在体内的表达动力学及记忆性T淋巴细胞反应的诱导

Geiben-Lynn, Ralf; Greenland, John R; Frimpong-Boateng, Kwesi; Letvin, Norman L

Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis

通过重组耻垢分枝杆菌启动快速诱导记忆性 CD8+ T 淋巴细胞

Hovav, Avi-Hai; Cayabyab, Mark J; Panas, Michael W; Santra, Sampa; Greenland, John; Geiben, Ralf; Haynes, Barton F; Jacobs, William R Jr; Letvin, Norman L

Plasmid DNA vaccine-elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis

质粒 DNA 疫苗引起的细胞免疫反应通过 Fas 介导的细胞凋亡限制体内疫苗抗原的表达

John R Greenland, Ralf Geiben, Sharmistha Ghosh, William A Pastor, Norman L Letvin

Noncytolytic inhibition of X4 virus by bulk CD8(+) cells from human immunodeficiency virus type 1 (HIV-1)-infected persons and HIV-1-specific cytotoxic T lymphocytes is not mediated by beta-chemokines

来自人类免疫缺陷病毒1型(HIV-1)感染者的大量CD8(+)细胞和HIV-1特异性细胞毒性T淋巴细胞对X4病毒的非细胞溶解性抑制作用并非由β-趋化因子介导。

R Geiben-Lynn ,M Kursar, N V Brown, E L Kerr, A D Luster, B D Walker