日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anti-CD38 monoclonal antibody interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping

抗CD38单克隆抗体干扰血液相容性检测:通过功能性表位定位区分isatuximab和daratumumab

Btissam Chami ,Makoto Okuda ,Morvarid Moayeri ,France Pirenne ,Yoko Hidaka ,Ashok Nambiar ,Zhili Song ,Olivier Bedel ,Bailin Zhang ,Joern Hopke ,Gejing Deng ,Chen Zhu ,Sandrine Macé ,Marielle Chiron ,Francisco Adrian ,Taro Fukao ,Frank G Basile ,Thomas Martin

Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

谷氨酰胺酶对于谷氨酰胺代谢途径失调的三阴性乳腺癌细胞的生长至关重要,其抑制与 mTOR 抑制有协同作用

Michael Lampa, Heike Arlt, Timothy He, Beatriz Ospina, Jason Reeves, Bailin Zhang, Joshua Murtie, Gejing Deng, Claude Barberis, Dietmar Hoffmann, Hong Cheng, Jack Pollard, Christopher Winter, Victoria Richon, Carlos Garcia-Escheverria, Francisco Adrian, Dmitri Wiederschain, Lakshmi Srinivasan

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

IDH1 突变癌症极易受到 NAD+ 耗竭的影响

Kensuke Tateishi, Hiroaki Wakimoto, A John Iafrate, Shota Tanaka, Franziska Loebel, Nina Lelic, Dmitri Wiederschain, Olivier Bedel, Gejing Deng, Bailin Zhang, Timothy He, Xu Shi, Robert E Gerszten, Yiyun Zhang, Jing-Ruey J Yeh, William T Curry, Dan Zhao, Sudhandra Sundaram, Fares Nigim, Mara V A Koe

Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule

通过变构小分子破坏金属结合网络选择性抑制突变异柠檬酸脱氢酶 1 (IDH1)

Gejing Deng, Junqing Shen, Ming Yin, Jessica McManus, Magali Mathieu, Patricia Gee, Timothy He, Chaomei Shi, Olivier Bedel, Larry R McLean, Frank Le-Strat, Ying Zhang, Jean-Pierre Marquette, Qiang Gao, Bailin Zhang, Alexey Rak, Dietmar Hoffmann, Eamonn Rooney, Aurelie Vassort, Walter Englaro, Yi Li,

Identification of elongation factor G as the conserved cellular target of argyrin B

确定延长因子 G 是 argyrin B 的保守细胞靶点

Beat Nyfeler, Dominic Hoepfner, Deborah Palestrant, Christina A Kirby, Lewis Whitehead, Robert Yu, Gejing Deng, Ruth E Caughlan, Angela L Woods, Adriana K Jones, S Whitney Barnes, John R Walker, Swann Gaulis, Ervan Hauy, Saskia M Brachmann, Philipp Krastel, Christian Studer, Ralph Riedl, David Estop

Biophysical investigation of the mode of inhibition of tetramic acids, the allosteric inhibitors of undecaprenyl pyrophosphate synthase

十一烯基焦磷酸合酶变构抑制剂特特拉姆酸抑制方式的生物物理研究

Lac V Lee, Brian Granda, Karl Dean, Jianshi Tao, Eugene Liu, Rui Zhang, Stefan Peukert, Sompong Wattanasin, Xiaoling Xie, Neil S Ryder, Ruben Tommasi, Gejing Deng