Gekle相关文献与解析，生知库 | 链接生命科学的每一步

Walendy, Victor; Gekle, Michael; Grossmann, Claudia; Kluttig, Alexander; Kraus, Frank Bernhard; Ludwig-Kraus, Beatrice; Mikolajczyk, Rafael; Schmid, Thomas; Thews, Oliver; Wienke, Andreas; Zinkhan, Melanie; Girndt, Matthias

动脉粥样硬化

发表日期：2026

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Occupational risk factors for depression and anxiety symptoms: Insights from a large cohort study during and after the SARS-CoV-2 pandemic

职业因素与抑郁和焦虑症状：一项在SARS-CoV-2大流行期间及之后开展的大型队列研究的启示

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0346871

Casjens, Swaantje; Hovanec, Jan; Glaser, Nadine; Massag, Janka; Pfrommer, Laura; Opel, Nils; Karch, André; Muellmann, Saskia; Moor, Irene; Gekle, Michael; Girndt, Matthias; Hettmer, Simone; Höll, Jessica I; Heuser, Michael; Frese, Thomas; Mikolajczyk, Rafael; Behrens, Thomas

Acidosis-induced p38-kinase activation triggers an IL-6-mediated crosstalk of renal proximal tubule cells with fibroblasts leading to their inflammatory response.

酸中毒诱导的 p38 激酶激活触发 IL-6 介导的肾近端小管细胞与成纤维细胞的串扰，从而导致其炎症反应

期刊:Cell Communication and Signaling

影响因子:8.9

doi:10.1186/s12964-025-02180-5

Schulz Marie-Christin, Wolff Nathalie, Kopf Michael, Gekle Micheal

Early-phase impact of obesity-associated stress on murine vascular smooth muscle cells depends on EGFR and sex

肥胖相关应激对小鼠血管平滑肌细胞的早期影响取决于EGFR和性别

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-09416-7

Dubourg, Virginie; Rabe, Sindy; Nasiri-Ansari, Narjes; Kopf, Michael; Mildenberger, Sigrid; Schwerdt, Gerald; Schreier, Barbara; Gekle, Michael

Post-COVID recovery is faster after an infection with the SARS-CoV-2 Omicron variant: a population-based cohort study

感染SARS-CoV-2 Omicron变异株后，新冠肺炎康复速度更快：一项基于人群的队列研究

期刊:Infection

影响因子:3.6

doi:10.1007/s15010-024-02438-z

Pfrommer, Laura Rebecca; Diexer, Sophie; Klee, Bianca; Massag, Janka; Gottschick, Cornelia; Purschke, Oliver; Binder, Mascha; Frese, Thomas; Girndt, Matthias; Sedding, Daniel; Rosendahl, Jonas; Hoell, Jessica I; Moor, Irene; Gekle, Michael; Allwang, Christine; Junne, Florian; Mikolajczyk, Rafael

Household transmission of Omicron variant of SARS-CoV-2 under conditions of hybrid immunity-a prospective study in Germany

德国一项前瞻性研究探讨了混合免疫条件下SARS-CoV-2 Omicron变异株的家庭传播情况。

期刊:Infection

影响因子:3.6

doi:10.1007/s15010-024-02352-4

Klee, Bianca; Diexer, Sophie; Xu, Chao; Gottschick, Cornelia; Hartmann, Carla; Meyer-Schlinkmann, Kristin Maria; Kuhlmann, Alexander; Rosendahl, Jonas; Binder, Mascha; Gekle, Michael; Girndt, Matthias; Höll, Jessica I; Moor, Irene; Sedding, Daniel; Moritz, Stefan; Frese, Thomas; Mikolajczyk, Rafael

Physiological serum uric acid concentrations correlate with arterial stiffness in a sex-dependent manner

生理性血清尿酸浓度与动脉僵硬度呈性别依赖性相关。

期刊:BMC Medicine

影响因子:

doi:10.1186/s12916-025-04195-8

Thews, Oliver; Schmid, Thomas; Kluttig, Alexander; Wienke, Andreas; Zinkhan, Melanie; Ahrens, Wolfgang; Bärnighausen, Till; Brenner, Hermann; Castell, Stefanie; Lange, Berit; Lieb, Wolfgang; Greiser, Karin Halina; Dörr, Marcus; Krist, Lilian; Willich, Stefan N; Harth, Volker; Obi, Nadia; Leitzmann, Michael; Peters, Annette; Schmidt, Börge; Schulze, Matthias B; Völzke, Henry; Nauck, Matthias; Zylla, Stephanie; Hannemann, Anke; Pischon, Tobias; Velásquez, Ilais Moreno; Girndt, Matthias; Grossmann, Claudia; Gekle, Michael

发表日期：2025

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Nominally identical microplastic models differ greatly in their particle-cell interactions

名义上相同的微塑料模型在颗粒-细胞相互作用方面存在显著差异。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-45281-4

Wieland, Simon; Ramsperger, Anja F R M; Gross, Wolfgang; Lehmann, Moritz; Witzmann, Thomas; Caspari, Anja; Obst, Martin; Gekle, Stephan; Auernhammer, Günter K; Fery, Andreas; Laforsch, Christian; Kress, Holger

细胞生物学

发表日期：2024

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The synergism of cytosolic acidosis and reduced NAD(+)/NADH ratio is responsible for lactic acidosis-induced vascular smooth muscle cell impairment in sepsis

胞质酸中毒和 NAD(+)/NADH 比值降低的协同作用是脓毒症中乳酸酸中毒诱导血管平滑肌细胞损伤的原因。

期刊:Journal of Biomedical Science

影响因子:12.1

doi:10.1186/s12929-023-00992-6

Terpe, Philipp; Ruhs, Stefanie; Dubourg, Virginie; Bucher, Michael; Gekle, Michael

Crosstalk with renal proximal tubule cells drives acidosis-induced inflammatory response and dedifferentiation of fibroblasts via p38-singaling

与肾近端小管细胞的相互作用通过p38信号通路驱动酸中毒诱导的炎症反应和成纤维细胞去分化

期刊:Cell Communication and Signaling

影响因子:8.9

doi:10.1186/s12964-024-01527-8

Schulz, Marie-Christin; Kopf, Michael; Gekle, Michael

Very low-grade albuminuria is linked to arterial stiffness in a population-based cohort

在一项基于人群的队列研究中，极低度蛋白尿与动脉硬化有关。

Occupational risk factors for depression and anxiety symptoms: Insights from a large cohort study during and after the SARS-CoV-2 pandemic

职业因素与抑郁和焦虑症状：一项在SARS-CoV-2大流行期间及之后开展的大型队列研究的启示

Acidosis-induced p38-kinase activation triggers an IL-6-mediated crosstalk of renal proximal tubule cells with fibroblasts leading to their inflammatory response.

酸中毒诱导的 p38 激酶激活触发 IL-6 介导的肾近端小管细胞与成纤维细胞的串扰，从而导致其炎症反应

Early-phase impact of obesity-associated stress on murine vascular smooth muscle cells depends on EGFR and sex

肥胖相关应激对小鼠血管平滑肌细胞的早期影响取决于EGFR和性别

Post-COVID recovery is faster after an infection with the SARS-CoV-2 Omicron variant: a population-based cohort study

感染SARS-CoV-2 Omicron变异株后，新冠肺炎康复速度更快：一项基于人群的队列研究

Household transmission of Omicron variant of SARS-CoV-2 under conditions of hybrid immunity-a prospective study in Germany

德国一项前瞻性研究探讨了混合免疫条件下SARS-CoV-2 Omicron变异株的家庭传播情况。

Physiological serum uric acid concentrations correlate with arterial stiffness in a sex-dependent manner

生理性血清尿酸浓度与动脉僵硬度呈性别依赖性相关。

Nominally identical microplastic models differ greatly in their particle-cell interactions

名义上相同的微塑料模型在颗粒-细胞相互作用方面存在显著差异。

The synergism of cytosolic acidosis and reduced NAD(+)/NADH ratio is responsible for lactic acidosis-induced vascular smooth muscle cell impairment in sepsis

胞质酸中毒和 NAD(+)/NADH 比值降低的协同作用是脓毒症中乳酸酸中毒诱导血管平滑肌细胞损伤的原因。

Crosstalk with renal proximal tubule cells drives acidosis-induced inflammatory response and dedifferentiation of fibroblasts via p38-singaling

与肾近端小管细胞的相互作用通过p38信号通路驱动酸中毒诱导的炎症反应和成纤维细胞去分化