Acidosis-induced p38-kinase activation triggers an IL-6-mediated crosstalk of renal proximal tubule cells with fibroblasts leading to their inflammatory response.

酸中毒诱导的 p38 激酶激活触发 IL-6 介导的肾近端小管细胞与成纤维细胞的串扰，从而导致其炎症反应