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Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study

HIV-1感染单核细胞后，HIV病毒血症或CCR5诱导的视网膜母细胞瘤蛋白表达可介导对激活诱导细胞凋亡的保护作用：离体和体外研究

Gekonge, Bethsebah; Raymond, Andrea D; Yin, Xiangfan; Kostman, Jay; Mounzer, Karam; Collman, Ronald G; Showe, Louise; Montaner, Luis J

凋亡

Constitutive gene expression in monocytes from chronic HIV-1 infection overlaps with acute Toll-like receptor induced monocyte activation profiles

慢性 HIV-1 感染单核细胞中的组成基因表达与急性 Toll 样受体诱导的单核细胞活化谱重叠

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0041153

Bethsebah Gekonge, Malavika S Giri, Andrew V Kossenkov, Michael Nebozyhn, Malik Yousef, Karam Mounzer, Louise Showe, Luis J Montaner

Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor-related apoptosis-inducing ligand

尽管肿瘤坏死因子相关的凋亡诱导配体被诱导，浆细胞样树突状细胞仍无法直接裂解 HIV 感染的自体 CD4+ T 细胞

期刊:Journal of Virology

影响因子:4

doi:10.1128/JVI.01350-09

Jihed Chehimi, Emmanouil Papasavvas, Costin Tomescu, Bethsebah Gekonge, Shaheed Abdulhaqq, Andrea Raymond, Aidan Hancock, Kavita Vinekar, Craig Carty, Griffin Reynolds, Maxwell Pistilli, Karam Mounzer, Jay Kostman, Luis J Montaner

Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia

HIV 病毒血症期间循环单核细胞中金属硫蛋白基因表达、锌和锌依赖性抗凋亡能力增加

期刊:Journal of Leukocyte Biology

影响因子:3.6

doi:10.1189/jlb.0110051

Andrea D Raymond, Bethsebah Gekonge, Malavika S Giri, Aidan Hancock, Emmanouil Papasavvas, Jihed Chehimi, Andrew V Kossenkov, Calen Nicols, Malik Yousef, Karam Mounzer, Jane Shull, Jay Kostman, Louise Showe, Luis J Montaner

Circulating monocytes in HIV-1-infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance

HIV-1 感染病毒血症患者的循环单核细胞表现出抗凋亡基因特征以及病毒和宿主介导的凋亡抵抗

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.0801450

Malavika S Giri, Michael Nebozyhn, Andrea Raymond, Bethsebah Gekonge, Aidan Hancock, Shenoa Creer, Calen Nicols, Malik Yousef, Andrea S Foulkes, Karam Mounzer, Jane Shull, Guido Silvestri, Jay Kostman, Ronald G Collman, Louise Showe, Luis J Montaner

Short communication: Nitazoxanide inhibits HIV viral replication in monocyte-derived macrophages

简讯：硝唑尼特抑制单核细胞来源巨噬细胞中的HIV病毒复制

Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study

HIV-1感染单核细胞后，HIV病毒血症或CCR5诱导的视网膜母细胞瘤蛋白表达可介导对激活诱导细胞凋亡的保护作用：离体和体外研究

Constitutive gene expression in monocytes from chronic HIV-1 infection overlaps with acute Toll-like receptor induced monocyte activation profiles

慢性 HIV-1 感染单核细胞中的组成基因表达与急性 Toll 样受体诱导的单核细胞活化谱重叠

Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor-related apoptosis-inducing ligand

尽管肿瘤坏死因子相关的凋亡诱导配体被诱导，浆细胞样树突状细胞仍无法直接裂解 HIV 感染的自体 CD4+ T 细胞

Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia

HIV 病毒血症期间循环单核细胞中金属硫蛋白基因表达、锌和锌依赖性抗凋亡能力增加

Circulating monocytes in HIV-1-infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance

HIV-1 感染病毒血症患者的循环单核细胞表现出抗凋亡基因特征以及病毒和宿主介导的凋亡抵抗