日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prolonging parathyroid hormone analog action in vitro and in vivo through peptide lipidation.

通过肽脂化延长甲状旁腺激素类似物在体外和体内的作用

Höppner Jakob, Noda Hiroshi, Anitha Anju Krishnan, Cheloha Ross W, Dean Thomas, Bruce Michael, Brooks Daniel J, Mannstadt Michael, Bouxsein Mary L, Gellman Samuel H, Khatri Ashok, Jüppner Harald, Gardella Thomas J

Dual Activation Modes Enable Bifunctional Catalysis of Aldol Reactions by Flexible Dihydrazides

双重活化模式使柔性二酰肼能够实现羟醛缩合反应的双功能催化

Lampkin, Philip P; Gellman, Samuel H

Bifunctional Catalysis of Aldol Reactions by Foldamer Dihydrazides: Assessment of Conformational Preorganization

折叠体二酰肼对羟醛缩合反应的双功能催化:构象预组织的评估

Lampkin, Philip P; Sanders, Kyana M; Garman, Leah C; Guzei, Ilia A; Gellman, Samuel H

Rational Design of a Foldon-Derived Heterotrimer Guided by Quantitative Native Mass Spectrometry

定量天然质谱指导的折叠子衍生异三聚体的合理设计

Liu, Xinyu; Roberts, David S; Bingman, Craig A; Ge, Ying; Gellman, Samuel H

Prolonged signaling of backbone-modified glucagon-like peptide-1 analogues with diverse receptor trafficking

骨架修饰的胰高血糖素样肽-1类似物通过多种受体转运实现延长信号传导

Cary, Brian P; Hager, Marlies V; Mariam, Zamara; Morris, Rylie K; Belousoff, Matthew J; Deganutti, Giuseppe; Sexton, Patrick M; Wootten, Denise; Gellman, Samuel H

A mouse model of Jansen's metaphyseal chondrodysplasia for investigating disease mechanisms and candidate therapeutics.

詹森氏干骺端软骨发育不良的小鼠模型,用于研究疾病机制和候选疗法

Höppner Jakob, Firat Damla, Parvez-Khan Mohd, Reyes Monica, Hanna Patrick, Yadav Prem Swaroop, Dean Thomas, Ramos-Torres Karla M, Brugarolas Pedro, Collins Michael T, Wein Marc N, Liu Shi, Gellman Samuel H, Schipani Ernestina, Kronenberg Henry M, Gardella Thomas J, Jüppner Harald

Enhancing Cancer Vaccine Efficacy: Backbone Modification with β‑Amino Acids Alters the Stability and Immunogenicity of MUC1-Derived Glycopeptide Formulations.

增强癌症疫苗功效:β-氨基酸修饰骨架可改变MUC1衍生糖肽制剂的稳定性和免疫原性

Gibadullin Ruslan, Suárez Óscar, Lazaris Foivos S, Gutiez Naiara, Atondo Estibaliz, Araujo-Aris Sarai, Eguskiza Ander, Niu Jiani, Kuhn Ariel J, Grosso Ana S, Rodriguez Héctor, García-Martín Fayna, Marcelo Filipa, Santos Tanausú, Avenoza Alberto, Busto Jesús H, Peregrina Jesús M, Gellman Samuel H, Anguita Juan, Fiammengo Roberto, Corzana Francisco

β-amino acid substitution in the SIINFEKL antigen alters immunological recognition.

SIINFEKL 抗原中的β-氨基酸替换会改变免疫识别

Rastogi Ichwaku, Mannone John A, Gibadullin Ruslan, Moseman Jena E, Sidney John, Sette Alessandro, McNeel Douglas G, Gellman Samuel H

Enhancing the solubility of SARS-CoV-2 inhibitors to increase future prospects for clinical development

提高SARS-CoV-2抑制剂的溶解度,以增加其未来临床开发前景。

Kuhn, Ariel J; Outlaw, Victor K; Marcink, Tara C; Yu, Zhen; Mears, Megan C; Cajimat, Maria N; Kreitler, Dale F; Cleven, Payton R; Mook, Jee Ching; Bente, Dennis A; Porotto, Matteo; Gellman, Samuel H; Moscona, Anne

Effects of D-Amino Acid Replacements on the Conformational Stability of Miniproteins

D-氨基酸取代对微蛋白构象稳定性的影响

Xu, Ruiwen; Huang, Jiawen; Kuhn, Ariel J; Gellman, Samuel H