日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vivo Immune-Modulatory Activity of Lefamulin in an Influenza Virus A (H1N1) Infection Model in Mice

来法莫林在小鼠甲型流感病毒(H1N1)感染模型中的体内免疫调节活性

Paukner, Susanne; Kimber, Sandra; Cumper, Charlotte; Rea-Davies, Tina; Sueiro Ballesteros, Lorena; Kirkham, Christopher; Hargreaves, Adam; Gelone, Steven P; Richards, Claire; Wicha, Wolfgang W

Physiologically-based pharmacokinetic modeling of the drug-drug interaction between ivacaftor and lefamulin in cystic fibrosis patients

基于生理的药代动力学模型研究伊伐卡托和来法莫林在囊性纤维化患者中的药物相互作用

Amiel, Magali; Ke, Alice; Gelone, Steven P; Jones, Hannah M; Wicha, Wolfgang

Improving Traditional Registrational Trial End Points: Development and Application of a Desirability of Outcome Ranking End Point for Complicated Urinary Tract Infection Clinical Trials

改进传统注册试验终点:复杂性尿路感染临床试验中结果期望排序终点的开发与应用

Howard-Anderson, Jessica; Hamasaki, Toshimitsu; Dai, Weixiao; Collyar, Deborah; Rubin, Daniel; Nambiar, Sumathi; Kinamon, Tori; Hill, Carol; Gelone, Steven P; Mariano, David; Baba, Takamichi; Holland, Thomas L; Doernberg, Sarah B; Chambers, Henry F; Fowler, Vance G; Evans, Scott R; Boucher, Helen W

Tissue Distribution of [(14)C]-Lefamulin into the Urogenital Tract in Rats

[(14)C]-来法莫林在大鼠泌尿生殖道中的组织分布

Wicha, Wolfgang W; Henson, Claire; Webbley, Kathryn; Gelone, Steven P

A plain language summary of how lefamulin alone can be used to treat pneumonia caught outside of the hospital due to common bacterial causes, including drug-resistant bacteria

本文以通俗易懂的语言概述了如何单独使用来法莫林治疗由常见细菌(包括耐药菌)引起的院外肺炎。

Paukner, Susanne; Moran, Gregory J; Sandrock, Christian; File, Thomas M Jr; Vidal, Jorge E; Waites, Ken B; Gelone, Steven P; Yu, Kalvin

Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model

来法莫林与阿奇霉素和地塞米松在脂多糖诱导的肺中性粒细胞增多症小鼠模型中的体内和体外抗炎活性

Michael Hafner, Susanne Paukner, Wolfgang W Wicha, Boška Hrvačić, Matea Cedilak, Ivan Faraho, Steven P Gelone

Erratum to: Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin Evaluation Against Pneumonia (LEAP 1) Trial

勘误:静脉注射转口服来法莫林(一种截短侧耳素类抗生素)治疗社区获得性细菌性肺炎的疗效和安全性:来法莫林抗肺炎 III 期评估 (LEAP 1) 试验

File, Thomas M; Goldberg, Lisa; Das, Anita; Sweeney, Carolyn; Saviski, John; Gelone, Steven P; Seltzer, Elyse; Paukner, Susanne; Wicha, Wolfgang W; Talbot, George H; Gasink, Leanne B

Influenza vaccines: the potential benefits of cell-culture isolation and manufacturing

流感疫苗:细胞培养分离和生产的潜在益处

Rajaram, Sankarasubramanian; Boikos, Constantina; Gelone, Daniele K; Gandhi, Ashesh

Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin Evaluation Against Pneumonia (LEAP 1) Trial

静脉注射转口服来法莫林(一种截短侧耳素类抗生素)治疗社区获得性细菌性肺炎的疗效和安全性:来法莫林抗肺炎III期评估(LEAP 1)试验

File, Thomas M; Goldberg, Lisa; Das, Anita; Sweeney, Carolyn; Saviski, John; Gelone, Steven P; Seltzer, Elyse; Paukner, Susanne; Wicha, Wolfgang W; Talbot, George H; Gasink, Leanne B

Low Prevalence of Gram-Positive Isolates Showing Elevated Lefamulin MIC Results during the SENTRY Surveillance Program for 2015-2016 and Characterization of Resistance Mechanisms

2015-2016 年 SENTRY 监测计划中革兰氏阳性分离株对来法莫林 MIC 结果升高的低流行率及其耐药机制特征

Mendes, Rodrigo E; Paukner, Susanne; Doyle, Timothy B; Gelone, Steven P; Flamm, Robert K; Sader, Helio S