日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair

基于增强子的基因治疗策略,用于组织修复过程中货物的时空控制

Ruorong Yan, Valentina Cigliola, Kelsey A Oonk, Zachary Petrover, Sophia DeLuca, David W Wolfson, Andrew Vekstein, Michelle A Mendiola, Garth Devlin, Muath Bishawi, Matthew P Gemberling, Tanvi Sinha, Michelle A Sargent, Allen J York, Avraham Shakked, Paige DeBenedittis, David C Wendell, Jianhong Ou,

Transgenic mice for in vivo epigenome editing with CRISPR-based systems

利用基于 CRISPR 的系统进行体内表观基因组编辑的转基因小鼠

Matthew P Gemberling #, Keith Siklenka #, Erica Rodriguez, Katherine R Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F Hazlett, Courtney A Williams, Luke C Bartelt, Victoria J Madigan, Josephine C Bodle, Heather Daniels, Douglas C Rouse, Isaac B Hilt

Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy

AAV-CRISPR 基因组编辑对杜氏肌营养不良症的长期评估

Christopher E Nelson, Yaoying Wu, Matthew P Gemberling, Matthew L Oliver, Matthew A Waller, Joel D Bohning, Jacqueline N Robinson-Hamm, Karen Bulaklak, Ruth M Castellanos Rivera, Joel H Collier, Aravind Asokan, Charles A Gersbach

RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors

利用金黄色葡萄球菌 CRISPR-Cas9 抑制剂进行 RNA 引导的体内转录沉默

Pratiksha I Thakore, Jennifer B Kwon, Christopher E Nelson, Douglas C Rouse, Matthew P Gemberling, Matthew L Oliver, Charles A Gersbach

Boosting, Not Breaking: CRISPR Activators Treat Disease Models

增强而非破坏:CRISPR激活剂治疗疾病模型

Gemberling, Matthew; Gersbach, Charles A

Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2.

缺氧期间 DAP5 诱导的 PHD2 翻译对缺氧诱导因子 1α 的调节

Bryant Jeffrey D, Brown Michael C, Dobrikov Mikhail I, Dobrikova Elena Y, Gemberling Sarah L, Zhang Qing, Gromeier Matthias

Loss-of-function genetic tools for animal models: cross-species and cross-platform differences

用于动物模型的基因功能缺失工具:跨物种和跨平台差异

Housden, Benjamin E; Muhar, Matthias; Gemberling, Matthew; Gersbach, Charles A; Stainier, Didier Y R; Seydoux, Geraldine; Mohr, Stephanie E; Zuber, Johannes; Perrimon, Norbert

Resolving Heart Regeneration by Replacement Histone Profiling

通过替代组蛋白谱分析解决心脏再生问题

Goldman, Joseph Aaron; Kuzu, Guray; Lee, Nutishia; Karasik, Jaclyn; Gemberling, Matthew; Foglia, Matthew J; Karra, Ravi; Dickson, Amy L; Sun, Fei; Tolstorukov, Michael Y; Poss, Kenneth D

Modulation of tissue repair by regeneration enhancer elements.

通过再生增强因子调节组织修复

Kang Junsu, Hu Jianxin, Karra Ravi, Dickson Amy L, Tornini Valerie A, Nachtrab Gregory, Gemberling Matthew, Goldman Joseph A, Black Brian L, Poss Kenneth D

Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration

单心外膜细胞转录组测序确定 Caveolin 1 是斑马鱼心脏再生的重要因素

Jingli Cao, Adam Navis, Ben D Cox, Amy L Dickson, Matthew Gemberling, Ravi Karra, Michel Bagnat, Kenneth D Poss