日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigation of a clinical trial drug VV261 as a potent antiviral candidate against Chikungunya virus

对临床试验药物VV261作为对抗基孔肯雅病毒的有效抗病毒候选药物进行研究

Zhang, Yumin; Tang, Sheng; Chen, Lu; Song, Shufen; Cao, Junyuan; Tian, Guanghui; Xiao, Gengfu; Shen, Jingshan; Zhang, Leike

FDA-approved IMPDH inhibitors synergize with ribavirin to inhibit respiratory syncytial virus by interfering with purine de novo synthesis

FDA批准的IMPDH抑制剂与利巴韦林协同作用,通过干扰嘌呤从头合成来抑制呼吸道合胞病毒。

Hu, Huina; Wang, Qingxing; Ai, Qiangyun; Zhou, Peiwen; He, Yang; Ye, Zuodong; Ma, Kaixiong; Zhou, Minmin; Huang, Shanzhi; Wang, Lei; Qi, Nan; Xiao, Gengfu; Wang, Shaobo

A clinical SARS-CoV-2 Mpro inhibitor blocks replication of multiple enteroviruses and confers oral in vivo protection in animal models

一种临床SARS-CoV-2 Mpro抑制剂可阻断多种肠道病毒的复制,并在动物模型中提供口服体内保护作用。

Ye, Zhengyu; Dai, Wenhao; Zhang, Shaolin; Xiang, Yingchun; Wang, Jinlin; Zhang, Yumin; Cao, Wenyuan; Neyts, Johan; Li, Zuyi; Feng, Fan; Xiao, Gengfu; Liu, Hong; Cao, Junyuan; Zhang, Lei-Ke

Animal Models of Exercise and Cardiometabolic Disease

运动与心血管代谢疾病的动物模型

Dong, Gengfu; Ryan, Terence E; Esser, Karyn A

Discovery and mechanistic insights of dibenzoylmethane as a broad spectrum inhibitor of coronavirus.

二苯甲酰甲烷作为冠状病毒广谱抑制剂的发现和机制研究

Sun Yuan, Shu Xiaoyang, Chen Lu, Shang Weijuan, Zhang Yumin, Xiao Gengfu, Zhang Leike

Pirfenidone treatment improves ischemic muscle function in mice with chronic kidney disease.

吡非尼酮治疗可改善慢性肾病小鼠的缺血性肌肉功能。

Balestrieri Nicholas, Dong Gengfu, Ryan Terence E

Eltrombopag, an FDA-approved drug, inhibits dengue virus type 2 by targeting NS2B-NS3 protease.

艾曲波帕是一种经 FDA 批准的药物,它通过靶向 NS2B-NS3 蛋白酶来抑制 2 型登革病毒

Zhu Xuerui, Gao Xiao, Wu Yan, Lu Jia, Chen Xinlan, Zhao Chenshu, Li Haoyu, Zhang Zhongfa, Liu Shuwen, Xiao Gengfu, Pan Xiaoyan

Nicotinamide N-methyltransferase inhibition improves limb function in experimental peripheral artery disease.

烟酰胺N-甲基转移酶抑制剂可改善实验性外周动脉疾病的肢体功能。

Dong Gengfu, Choi Jaewon, Li Yufen, Muller Diana C, Li Zhuoxin, Luo Yangyi E, Ryan Terence E

Integrative analysis of the metabolomes and transcriptomes of Ebola virus-infected cells: Uncovering pathways related to hepatic apoptosis

埃博拉病毒感染细胞代谢组和转录组的整合分析:揭示与肝细胞凋亡相关的通路

Liu, Chenchen; Cao, Zengguo; Peng, Cheng; Li, Fangxu; Chen, Zixi; Zhang, Xinghai; Jia, Xiaoying; Zhou, Jinge; Mao, Wenting; Li, Entao; Xiao, Gengfu; Chiu, Sandra

A nanoluciferase SFTSV for rapid screening antivirals and real-time visualization of virus infection in mice

纳米荧光素酶 SFTSV 用于快速筛选抗病毒药物并实时可视化小鼠病毒感染

Huan Xu, Xiaoqin Jian, Yuxi Wen, Mengwei Xu, Runming Jin, Xiaoyan Wu, Fen Zhou, Junyuan Cao, Gengfu Xiao, Ke Peng, Yuanchao Xie, Hongbo Chen, Leike Zhang