日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

IL-18 metabolically reprograms CAR-expressing natural killer T cells and enhances their antitumor activity.

IL-18 通过代谢重编程表达 CAR 的自然杀伤 T 细胞，增强其抗肿瘤活性。

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2026.01.001
Barragán Bravo Gabriel A, de la Cerda David A, Landoni Elisa, Dholakia Kshiti, Humeniuk Piotr, Caraballo Galva Leidy D, Wang Ying, Tian Gengwen, Yang Boning, Guo Linjie, Wood Michael S, Rios Xavier, Xu Xin, Courtney Amy N, Di Pierro Erica J, Jacob Joan, Li Yi-Han, Adaikkalavan Akshaya, Watanabe Norihiro, Mao Sufeng, Miles George, Dotti Gianpietro, Metelitsa Leonid S
肿瘤
T细胞
肿瘤免疫
代谢
代谢重编程
细胞生物学
IL-18
发表日期：2026
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Systematic Pathway Screening via Integrated Machine Learning Identifies FOXO-Mediated Transcription Signature for Robust Immunotherapy Response Prediction in Non-Small Cell Lung Cancer.

通过整合机器学习进行系统通路筛选，识别 FOXO 介导的转录特征，从而对非小细胞肺癌的免疫治疗反应进行稳健预测。

期刊:Human Mutation
影响因子:3.7
doi:10.1155/humu/8690530
Wu Shuqi, Deng Chenxi, Fan Chaofan, Liang Qiheng, Zhu Lingxuan, Mou Weiming, Huang Hongsen, Wu Keren, Li Yizhang, Deng Gengwen, Xu Liling, Xie Jiarui, Hong Chenglin, Deng Yuhang, Li Xingjian, Wu Changda, Yang Tao, Luo Peng, Wong Hank Z H, Jiang Aimin, Lin Anqi, Chen Xin, Ren Minghua
肺癌
细胞生物学
发表日期：2026
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Intratumoral mycobiome heterogeneity influences the tumor microenvironment and immunotherapy outcomes in renal cell carcinoma

肿瘤内真菌群落异质性影响肾细胞癌的肿瘤微环境和免疫治疗效果

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adu1727
Mou, Weiming; Deng, Zhixing; Zhu, Lingxuan; Jiang, Aimin; Lin, Anqi; Xu, Liling; Deng, Gengwen; Huang, Hongsen; Guo, Zeji; Zhu, Bang; Wu, Shuqi; Yang, Tao; Wang, Lu; Liu, Zaoqu; Wei, Ting; Zhang, Jian; Cheng, Liang; Huang, Haojie; Chen, Rui; Shao, Yi; Cheng, Quan; Wang, Linhui; Yuan, Shuofeng; Luo, Peng
肿瘤
肿瘤免疫
肾癌
微生物学
细胞生物学
肿瘤微环境
免疫/内分泌
发表日期：2025
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Hyperleukocytosis in a neuroblastoma patient after treatment with natural killer T cells expressing a GD2-specific chimeric antigen receptor and IL-15

神经母细胞瘤患者接受表达GD2特异性嵌合抗原受体和IL-15的自然杀伤T细胞治疗后出现白细胞增多症

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-010156
Tian, Gengwen; Courtney, Amy N; Yu, Hangjin; Bhar, Saleh; Xu, Xin; Barragán, Gabriel A; Martinez Amador, Claudia; Ghatwai, Nisha; Wood, Michael S; Schady, Deborah; Montalbano, Antonino; Reddy, Shantan; Roche, Aoife M; de la Cerda, David; Parsons, Donald Williams; Di Pierro, Erica J; Bushman, Frederic D; Heczey, Andras; Metelitsa, Leonid S
T细胞
信号转导
T细胞
细胞生物学
IL-15
免疫/内分泌
发表日期：2025
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Response to: Correspondence on "Hyperleukocytosis in a neuroblastoma patient after treatment with natural killer T cells expressing a GD2-specific chimeric antigen receptor and IL-15" by Ataca Atilla and Atilla

回复：Ataca Atilla 和 Atilla 的来信“用表达 GD2 特异性嵌合抗原受体和 IL-15 的自然杀伤 T 细胞治疗神经母细胞瘤患者后出现白细胞增多症”。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-011858
Tian, Gengwen; Courtney, Amy N; Heczey, Andras; Metelitsa, Leonid S
信号转导
细胞生物学
T细胞
IL-15
发表日期：2025
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Facts and Hopes of Chimeric Antigen Receptor-Redirected NK T Cells

嵌合抗原受体重定向NK T细胞的现状与前景

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-0197
Courtney, Amy N; Zhou, Xin; Tian, Gengwen; Wang, Ying; Metelitsa, Leonid S; Dotti, Gianpietro
T细胞
信号转导
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Development and validation of an explainable machine learning model for mortality prediction among patients with infected pancreatic necrosis

开发和验证用于预测感染性胰腺坏死患者死亡率的可解释机器学习模型

期刊:EClinicalMedicine
影响因子:10
doi:10.1016/j.eclinm.2025.103074
Ning, Caihong; Ouyang, Hui; Xiao, Jie; Wu, Di; Sun, Zefang; Liu, Baiqi; Shen, Dingcheng; Hong, Xiaoyue; Lin, Chiayan; Li, Jiarong; Chen, Lu; Zhu, Shuai; Li, Xinying; Xia, Fada; Huang, Gengwen
炎症/感染
发表日期：2025
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PRDM1 Is a Key Regulator of the NKT-cell Central Memory Program and Effector Function

PRDM1是NKT细胞中央记忆程序和效应功能的关键调节因子

期刊:Cancer Immunology Research
影响因子:8.1
doi:10.1158/2326-6066.CIR-24-0259
Gengwen Tian,Gabriel A Barragan,Hangjin Yu,Claudia Martinez-Amador,Akshaya Adaikkalavan,Xavier Rios,Linjie Guo,Janice M Drabek,Osmay Pardias,Xin Xu,Antonino Montalbano,Chunchao Zhang,Yanchuan Li,Amy N Courtney,Erica J Di Pierro,Leonid S Metelitsa
细胞生物学
T细胞
PRDM1
T细胞
发表日期：2025
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Clinical evaluation of probe capture-based targeted next-generation sequencing in suspected infected pancreatic necrosis: a prospective pilot diagnostic study

探针捕获靶向二代测序技术在疑似感染性胰腺坏死中的临床评价：一项前瞻性试点诊断研究

期刊:BMC Infectious Diseases
影响因子:3
doi:10.1186/s12879-025-12441-w
Liu, Baiqi; Shen, Dingcheng; Cao, Xintong; Hong, Xiaoyue; Lin, Chiayen; Guo, Rong; Sun, Zefang; Ning, Caihong; Chen, Lu; Yu, Yan; Li, Jiarong; Huang, Gengwen
炎症/感染
Sequencing
发表日期：2025
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Impact of the COVID-19 Pandemic on Multidrug-Resistant Organism Infections in Infected Pancreatic Necrosis: A Post-Hoc Cohort Analysis

COVID-19 大流行对感染性胰腺坏死患者多重耐药菌感染的影响：一项事后队列分析

期刊:Infection and Drug Resistance
影响因子:2.9
doi:10.2147/IDR.S535563
Liu, Baiqi; Ning, Caihong; Li, Jiarong; Sun, Zefang; Lin, Chiayen; Hong, Xiaoyue; Guo, Rong; Chen, Lu; Shen, Dingcheng; Huang, Gengwen
炎症/感染
发表日期：2025
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