日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metformin Prevents Tumor Cell Growth and Invasion of Human Hormone Receptor-Positive Breast Cancer (HR+ BC) Cells via FOXA1 Inhibition

二甲双胍通过抑制 FOXA1 来阻止肿瘤细胞生长和人类激素受体阳性乳腺癌 (HR+ BC) 细胞的侵袭

Christine Song, Dawa Jung, Ayse Tuba Kendi, Jin Kyung Rho, Eun-Joo Kim, Ian Horn, Geoffry L Curran, Sujala Ghattamaneni, Ji Yeon Shim, Pil Soo Kang, Daehun Kang, Jay B Thakkar, Sannidhi Dewan, Val J Lowe, Seung Baek Lee

High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid- β Distribution between Brain and Plasma

高密度脂蛋白模拟肽 4F 有效穿过血脑屏障并调节脑和血浆之间的淀粉样β蛋白分布

Suresh K Swaminathan, Andrew L Zhou, Kristen M Ahlschwede, Geoffry L Curran, Val J Lowe, Ling Li, Karunya K Kandimalla

Multimodal nanoprobes to target cerebrovascular amyloid in Alzheimer's disease brain

多模态纳米探针靶向阿尔茨海默病患者脑血管淀粉样蛋白

Kristen M Jaruszewski, Geoffry L Curran, Suresh K Swaminathan, Jens T Rosenberg, Samuel C Grant, Subramanian Ramakrishnan, Val J Lowe, Joseph F Poduslo, Karunya K Kandimalla

Engineering theranostic nanovehicles capable of targeting cerebrovascular amyloid deposits

设计能够靶向脑血管淀粉样蛋白沉积物的治疗诊断纳米载体

Edward K Agyare, Kristen M Jaruszewski, Geoffry L Curran, Jens T Rosenberg, Samuel C Grant, Val J Lowe, Subramanian Ramakrishnan, Anant K Paravastu, Joseph F Poduslo, Karunya K Kandimalla

Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brain

肽载体介导非共价递送未修饰的顺铂、甲氨蝶呤和其他药物通过静脉途径到达大脑

Gobinda Sarkar, Geoffry L Curran, Jann N Sarkaria, Val J Lowe, Robert B Jenkins

A carrier for non-covalent delivery of functional beta-galactosidase and antibodies against amyloid plaques and IgM to the brain

一种用于将功能性 β-半乳糖苷酶和抗淀粉样斑块和 IgM 抗体非共价递送至大脑的载体

Gobinda Sarkar, Geoffry L Curran, Eric Mahlum, Teresa Decklever, Thomas M Wengenack, Anthony Blahnik, Bridget Hoesley, Val J Lowe, Joseph F Poduslo, Robert B Jenkins

HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons

阿尔茨海默病 Abeta 的 HH 结构域为 PC12 和小鼠皮质/海马神经元中的神经元结合提供了结构基础

Joseph F Poduslo, Emily J Gilles, Muthu Ramakrishnan, Kyle G Howell, Thomas M Wengenack, Geoffry L Curran, Karunya K Kandimalla

Selective contrast enhancement of individual Alzheimer's disease amyloid plaques using a polyamine and Gd-DOTA conjugated antibody fragment against fibrillar Abeta42 for magnetic resonance molecular imaging

使用多胺和 Gd-DOTA 偶联抗体片段对纤维状 Abeta42 进行选择性对比增强,以进行磁共振分子成像

Muthu Ramakrishnan, Thomas M Wengenack, Karunya K Kandimalla, Geoffry L Curran, Emily J Gilles, Marina Ramirez-Alvarado, Joseph Lin, Michael Garwood, Clifford R Jack Jr, Joseph F Poduslo

Development of a smart nano-vehicle to target cerebrovascular amyloid deposits and brain parenchymal plaques observed in Alzheimer's disease and cerebral amyloid angiopathy

开发智能纳米载体以针对阿尔茨海默病和脑淀粉样血管病中观察到的脑血管淀粉样蛋白沉积和脑实质斑块

Edward K Agyare, Geoffry L Curran, Muthu Ramakrishnan, Caroline C Yu, Joseph F Poduslo, Karunya K Kandimalla