Georg Varga相关文献与解析，生知库 | 链接生命科学的每一步

Rebecca Rixen # ，Paula Schütz # ，Carolin Walter # ，Birte Hüchtmann ，Veerle Van Marck ，Barbara Heitplatz ，Julian Varghese ，Georg Varga ，Dirk Foell ，Thomas Pap ，Hermann Pavenstädt ，Konrad Buscher

毒理研究

肾损伤

免疫/内分泌

发表日期：2025

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Ascorbate mitigates oxidative stress and hemin cytotoxicity in heme oxygenase-1 deficiency

抗坏血酸可减轻血红素加氧酶-1缺乏症中的氧化应激和血红素细胞毒性。

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2025.110705

Lea-Sophie Berendes ，Petra Schulze Westhoff ，Ann-Marie Tobinski ，Jorge A Narvaez Pardo ，Victoria Wingert ，Manfred Fobker ，Saskia Biskup ，Anja Seelhöfer ，Veerle Van Marck ，Barbara Heitplatz ，Philip T Drell ，Helmut Wittkowski ，Anibh M Das ，Luciana Hannibal ，Witold N Nowak ，Alicja Józkowicz ，Luisa Klotz ，Georg Varga ，Thorsten Marquardt ，Julien Park

氧化应激

发表日期：2025

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Conversion of dendritic cells into tolerogenic or inflammatory cells depends on the activation threshold and kinetics of the mTOR signaling pathway

树突状细胞转化为耐受性细胞或炎症细胞取决于 mTOR 信号通路的激活阈值和动力学

期刊:Cell Communication and Signaling

影响因子:8.2

doi:10.1186/s12964-024-01655-1

Viktor Wixler, Yvonne Boergeling, Rafael Leite Dantas, Georg Varga, Stephan Ludwig

Clinical and molecular analysis of a novel variant in heme oxygenase-1 deficiency: Unraveling its role in inflammation, heme metabolism, and pulmonary phenotype

血红素加氧酶-1缺乏症新变异体的临床和分子分析：揭示其在炎症、血红素代谢和肺部表型中的作用

期刊:Molecular Genetics and Metabolism Reports

影响因子:1.8

doi:10.1016/j.ymgmr.2023.101038

Lea-Sophie Berendes ，Petra Schulze Westhoff ，Helmut Wittkowski ，Anja Seelhöfer ，Georg Varga ，Thorsten Marquardt ，Julien H Park

Small spleen peptides prevent development of psoriatic arthritis via restoration of peripheral tolerance

小脾肽通过恢复外周耐受性来预防银屑病关节炎的发展

期刊:Molecular Therapy

影响因子:12.1

doi:10.1016/j.ymthe.2021.08.030

Viktor Wixler, Igor Z Zaytsev, Rafael Leite Dantas, Tanja Schied, Yvonne Boergeling, Veronika Lührmann, Georg Varga, Dörthe Masemann, Stephan Ludwig

A myostatin-CCL20-CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis

肌生长抑制素-CCL20-CCR6 轴调节实验性关节炎中 Th17 细胞向发炎关节的募集

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-93599-6

Michelle Fennen, Toni Weinhage, Vanessa Kracke, Johanna Intemann, Georg Varga, Corinna Wehmeyer, Dirk Foell, Adelheid Korb-Pap, Thomas Pap, Berno Dankbar

Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages

溶瘤流感病毒感染恢复肺肿瘤相关肺泡巨噬细胞的免疫能力

期刊:Oncoimmunology

影响因子:

doi:10.1080/2162402X.2017.1423171

Dörthe Masemann, Katharina Köther, Meike Kuhlencord, Georg Varga, Johannes Roth, Brian Dennis Lichty, Ulf Rüdiger Rapp, Viktor Wixler, Stephan Ludwig

Granulocyte Macrophage Colony-Stimulating Factor-Activated CD39+/CD73+ Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T Cells

粒细胞巨噬细胞集落刺激因子激活的 CD39+/CD73+ 小鼠单核细胞通过诱导调节性 T 细胞来调节肠道炎症

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.1

doi:10.1016/j.jcmgh.2015.04.005

Toni Weinhage, Jan Däbritz, Anne Brockhausen, Timo Wirth, Markus Brückner, Michael Belz, Dirk Foell, Georg Varga

Immunology/Inflammation

发表日期：2015

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MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection

MAPKAP 激酶 3 抑制 Ifng 基因表达并减弱甲型流感病毒感染后的 NK 细胞细胞毒性和 Th1 CD4 T 细胞发育

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.14-249599

Katharina Köther, Carolin Nordhoff, Dörthe Masemann, Georg Varga, Jay H Bream, Matthias Gaestel, Viktor Wixler, Stephan Ludwig

Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils

金黄色葡萄球菌潘顿-瓦伦丁白细胞毒素是一种对人类中性粒细胞非常有效的细胞毒因子

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1000715

Bettina Löffler, Muzaffar Hussain, Matthias Grundmeier, Michaela Brück, Dirk Holzinger, Georg Varga, Johannes Roth, Barbara C Kahl, Richard A Proctor, Georg Peters

Microvascular immunity is organ-specific and remodeled after kidney injury in mice

小鼠的微血管免疫具有器官特异性，并在肾损伤后发生重塑。

Ascorbate mitigates oxidative stress and hemin cytotoxicity in heme oxygenase-1 deficiency

抗坏血酸可减轻血红素加氧酶-1缺乏症中的氧化应激和血红素细胞毒性。

Conversion of dendritic cells into tolerogenic or inflammatory cells depends on the activation threshold and kinetics of the mTOR signaling pathway

树突状细胞转化为耐受性细胞或炎症细胞取决于 mTOR 信号通路的激活阈值和动力学

Clinical and molecular analysis of a novel variant in heme oxygenase-1 deficiency: Unraveling its role in inflammation, heme metabolism, and pulmonary phenotype

血红素加氧酶-1缺乏症新变异体的临床和分子分析：揭示其在炎症、血红素代谢和肺部表型中的作用

Small spleen peptides prevent development of psoriatic arthritis via restoration of peripheral tolerance

小脾肽通过恢复外周耐受性来预防银屑病关节炎的发展

A myostatin-CCL20-CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis

肌生长抑制素-CCL20-CCR6 轴调节实验性关节炎中 Th17 细胞向发炎关节的募集

Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages

溶瘤流感病毒感染恢复肺肿瘤相关肺泡巨噬细胞的免疫能力

Granulocyte Macrophage Colony-Stimulating Factor-Activated CD39+/CD73+ Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T Cells

粒细胞巨噬细胞集落刺激因子激活的 CD39+/CD73+ 小鼠单核细胞通过诱导调节性 T 细胞来调节肠道炎症

MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection

MAPKAP 激酶 3 抑制 Ifng 基因表达并减弱甲型流感病毒感染后的 NK 细胞细胞毒性和 Th1 CD4 T 细胞发育

Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils

金黄色葡萄球菌潘顿-瓦伦丁白细胞毒素是一种对人类中性粒细胞非常有效的细胞毒因子