日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combinatorial regulation by ERK1/2 and CK1δ protein kinases leads to HIF-1α association with microtubules and facilitates its symmetrical distribution during mitosis.

ERK1/2 和 CK1α 蛋白激酶的组合调控导致 HIF-1α 与微管结合,并促进其在有丝分裂期间的对称分布

Arseni Christina, Samiotaki Martina, Panayotou George, Simos George, Mylonis Ilias

Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling

短期缺氧引发 ROS 和 SAFB 介导的核基质和 mRNA 剪接重塑

Chrysa Taze, Sotiria Drakouli, Martina Samiotaki, George Panayotou, George Simos, Eleni Georgatsou, Ilias Mylonis

Hepcidin as a Sensitive and Treatment-Responsive Acute-Phase Marker in Patients with Bacteremia: A Pilot Study

铁调素作为菌血症患者的敏感和治疗反应性急性期标志物:一项初步研究

Kreon Koukoulas, Vasiliki Lygoura, Philip Kartalidis, Nikolaos K Gatselis, Efthymia Petinaki, George N Dalekos, George Simos

ERK signaling controls productive HIF-1 binding to chromatin and cancer cell adaptation to hypoxia through HIF-1α interaction with NPM1

ERK信号通路通过HIF-1α与NPM1的相互作用,控制HIF-1与染色质的有效结合以及癌细胞对缺氧的适应。

Koukoulas, Kreon; Giakountis, Antonis; Karagiota, Angeliki; Samiotaki, Martina; Panayotou, George; Simos, George; Mylonis, Ilias

Quantitative Identification of Functional Connectivity Disturbances in Neuropsychiatric Lupus Based on Resting-State fMRI: A Robust Machine Learning Approach

基于静息态功能磁共振成像的神经精神性狼疮功能连接障碍定量识别:一种稳健的机器学习方法

Simos, Nicholas John; Dimitriadis, Stavros I; Kavroulakis, Eleftherios; Manikis, Georgios C; Bertsias, George; Simos, Panagiotis; Maris, Thomas G; Papadaki, Efrosini

HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia

HIF-1α衍生的细胞穿透肽抑制ERK依赖的HIF-1激活并引发缺氧条件下癌细胞凋亡

Angeliki Karagiota, Maria Kourti, George Simos, Ilias Mylonis

Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen

缺氧诱导的 SUMO 结合变化影响低氧条件下的转录调控

Georgia Chachami, Nicolas Stankovic-Valentin, Angeliki Karagiota, Angeliki Basagianni, Uwe Plessmann, Henning Urlaub, Frauke Melchior, George Simos

ERK1/2 phosphorylates HIF-2α and regulates its activity by controlling its CRM1-dependent nuclear shuttling

ERK1/2 磷酸化 HIF-2α,并通过控制 CRM1 依赖的核穿梭来调节其活性

Ioanna-Maria Gkotinakou, Christina Befani, George Simos, Panagiotis Liakos

Hypoxia Induces Pro-Fibrotic and Fibrosis Marker Genes in Hepatocellular Carcinoma Cells Independently of Inflammatory Stimulation and the NF-κΒ Pathway

缺氧独立于炎症刺激和 NF-κΒ 通路诱导肝细胞癌细胞中的促纤维化和纤维化标志基因

Eleni-Anastasia Triantafyllou, Ilias Mylonis, George Simos, Efrosyni Paraskeva

Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells

mTOR 复合物 1 下调 PERK 活性和 eIF2α 丝氨酸 51 磷酸化,在结节性硬化症缺陷细胞中引发促氧化和促死亡作用

Jothilatha Krishnamoorthy, Clara Tenkerian, Jyotsana Gupta, Nour Ghaddar, Shuo Wang, Cedric Darini, Kirk A Staschke, Abhishek Ghosh, Valentina Gandin, Ivan Topisirovic, Arnold S Kristof, Maria Hatzoglou, George Simos, Antonis E Koromilas