日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

De novo design of buttressed loops for sculpting protein functions

从头设计支撑环以塑造蛋白质功能

Hanlun Jiang # ,Kevin M Jude # ,Kejia Wu # ,Jorge Fallas ,George Ueda ,T J Brunette ,Derrick R Hicks ,Harley Pyles ,Aerin Yang ,Lauren Carter ,Mila Lamb ,Xinting Li ,Paul M Levine ,Lance Stewart ,K Christopher Garcia ,David Baker

Computational design of non-porous pH-responsive antibody nanoparticles

无孔pH响应抗体纳米粒子的计算设计

Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, 

Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera

融合前冠状病毒刺突的纳米粒子展示可引发针对不同冠状病毒亚属的 S1 交叉反应抗体反应

Geoffrey B Hutchinson #, Olubukola M Abiona #, Cynthia T Ziwawo, Anne P Werner, Daniel Ellis, Yaroslav Tsybovsky, Sarah R Leist, Charis Palandjian, Ande West, Ethan J Fritch, Nianshuang Wang, Daniel Wrapp, Seyhan Boyoglu-Barnum, George Ueda, David Baker, Masaru Kanekiyo, Jason S McLellan, Ralph S Ba

Quadrivalent influenza nanoparticle vaccines induce broad protection

四价流感纳米颗粒疫苗可产生广泛的保护作用

Seyhan Boyoglu-Barnum #, Daniel Ellis #, Rebecca A Gillespie, Geoffrey B Hutchinson, Young-Jun Park, Syed M Moin, Oliver J Acton, Rashmi Ravichandran, Mike Murphy, Deleah Pettie, Nick Matheson, Lauren Carter, Adrian Creanga, Michael J Watson, Sally Kephart, Sila Ataca, John R Vaile, George Ueda, Mic

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

通过免疫复合物或蛋白质纳米颗粒制剂将 HIV 包膜免疫原靶向非人类灵长类动物的 B 细胞滤泡

Jacob T Martin #, Christopher A Cottrell #, Aleksandar Antanasijevic #, Diane G Carnathan, Benjamin J Cossette, Chiamaka A Enemuo, Etse H Gebru, Yury Choe, Federico Viviano, Stephanie Fischinger, Talar Tokatlian, Kimberly M Cirelli, George Ueda, Jeffrey Copps, Torben Schiffner, Sergey Menis, Galit A

Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

定制设计蛋白质纳米颗粒支架用于病毒糖蛋白抗原的多价呈递

George Ueda #, Aleksandar Antanasijevic #, Jorge A Fallas, William Sheffler, Jeffrey Copps, Daniel Ellis, Geoffrey B Hutchinson, Adam Moyer, Anila Yasmeen, Yaroslav Tsybovsky, Young-Jun Park, Matthew J Bick, Banumathi Sankaran, Rebecca A Gillespie, Philip Jm Brouwer, Peter H Zwart, David Veesler, Ma

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

HIV Env 三聚体免疫原的全新设计的双组分纳米颗粒载体的结构和功能评估

Aleksandar Antanasijevic, George Ueda, Philip J M Brouwer, Jeffrey Copps, Deli Huang, Joel D Allen, Christopher A Cottrell, Anila Yasmeen, Leigh M Sewall, Ilja Bontjer, Thomas J Ketas, Hannah L Turner, Zachary T Berndsen, David C Montefiori, Per Johan Klasse, Max Crispin, David Nemazee, John P Moore

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

细胞因子受体信号传导的拓扑控制在造血过程中产生不同的影响

Kritika Mohan # ,George Ueda # ,Ah Ram Kim ,Kevin M Jude ,Jorge A Fallas ,Yu Guo ,Maximillian Hafer ,Yi Miao ,Robert A Saxton ,Jacob Piehler ,Vijay G Sankaran ,David Baker ,K Christopher Garcia