Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer
发现（噻吩并嘧啶-2-基）氨基嘧啶作为有效、选择性且可口服的泛 PI3-激酶和双重泛 PI3-激酶/mTOR 抑制剂，可用于治疗癌症
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm901284w
Daniel P Sutherlin, Deepak Sampath, Megan Berry, Georgette Castanedo, Zhigang Chang, Irina Chuckowree, Jenna Dotson, Adrian Folkes, Lori Friedman, Richard Goldsmith, Tim Heffron, Leslie Lee, John Lesnick, Cristina Lewis, Simon Mathieu, Jim Nonomiya, Alan Olivero, Jodie Pang, Wei Wei Prior, Laurent S
