日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Covalent Labeling of Matrix Metalloproteases with Affinity-Based Probes Containing Tuned Reactive N-Acyl-N-Alkyl Sulfonamide Cleavable Linkers

利用含有可调控反应性N-酰基-N-烷基磺酰胺可裂解连接子的亲和探针，对基质金属蛋白酶进行共价标记

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.202400441
Devel, Laurent; Malgorn, Carole; Tohon, Regis-William; Launay, Marie; Patiniotis, Konstantinos; Sejalon-Cipolla, Mylene; Beau, Fabrice; Thai, Robert; Bruyat, Pierrick; Bonino, Annabelle; Bregant, Sarah; Subra, Gilles; Cantel, Sonia; Georgiadis, Dimitris
信号转导
发表日期：2024
文献求助 收藏

Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

与结构域闭合和底物结合相关的构象动力学解释了ERAP1的变构调节机制。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-021-25564-w
Maben, Zachary; Arya, Richa; Georgiadis, Dimitris; Stratikos, Efstratios; Stern, Lawrence J
发表日期：2021
文献求助 收藏

The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class I.

ERAP1 活性位点无法有效地接触稳定结合在 MHC I 类分子上的抗原肽前体的 N 端

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-021-95786-x
Mavridis George, Mpakali Anastasia, Zoidakis Jerome, Makridakis Manousos, Vlahou Antonia, Kaloumenou Eleni, Ziotopoulou Angeliki, Georgiadis Dimitris, Papakyriakou Athanasios, Stratikos Efstratios
发表日期：2021
文献求助 收藏

Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes

MMP-12选择性光学探针的合成、体外和体内评价

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.6b00377
Bordenave, Thomas; Helle, Marion; Beau, Fabrice; Georgiadis, Dimitris; Tepshi, Livia; Bernes, Mylène; Ye, Yunpeng; Levenez, Laure; Poquet, Enora; Nozach, Hervé; Razavian, Mahmoud; Toczek, Jakub; Stura, Enrico A; Dive, Vincent; Sadeghi, Mehran M; Devel, Laurent
MMP-1
MMP-12
多发性骨髓瘤
发表日期：2016
文献求助 收藏

Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells

自身免疫性疾病相关的细胞外内质网氨肽酶1变异体可诱导人类免疫细胞产生改变的先天免疫反应

期刊:Journal of Innate Immunity
影响因子:3
doi:10.1159/000368899
Aldhamen, Yasser A; Pepelyayeva, Yuliya; Rastall, David P W; Seregin, Sergey S; Zervoudi, Efthalia; Koumantou, Despoina; Aylsworth, Charles F; Quiroga, Dionisia; Godbehere, Sarah; Georgiadis, Dimitris; Stratikos, Efstratios; Amalfitano, Andrea
自身免疫性疾病
免疫/内分泌
细胞生物学
发表日期：2015
文献求助 收藏

Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses

合理设计的靶向抗原修饰氨肽酶的抑制剂可增强抗原呈递和细胞毒性T细胞反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1309781110
Zervoudi, Efthalia; Saridakis, Emmanuel; Birtley, James R; Seregin, Sergey S; Reeves, Emma; Kokkala, Paraskevi; Aldhamen, Yasser A; Amalfitano, Andrea; Mavridis, Irene M; James, Edward; Georgiadis, Dimitris; Stratikos, Efstratios
T细胞
T细胞
细胞生物学
毒理研究
免疫/内分泌
发表日期：2013
文献求助 收藏

Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.

从针对 MMP-12 的选择性非膦酸抑制剂中获得的见解，这些抑制剂经过专门设计以适应 S1' 环的典型构象

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M110.139634
Devel Laurent, Garcia Sandra, Czarny Bertrand, Beau Fabrice, LaJeunesse Evelyne, Vera Laura, Georgiadis Dimitris, Stura Enrico, Dive Vincent
其它
发表日期：2010
文献求助 收藏