日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TBCRC 035: randomized phase II pharmacodynamic study of standard and reduced-dose palbociclib with endocrine therapy in hormone receptor (HR)-positive previously treated metastatic breast cancer

TBCRC 035:一项随机 II 期药效学研究,评估标准剂量和减量帕博西尼联合内分泌治疗在激素受体 (HR) 阳性、既往接受过治疗的转移性乳腺癌患者中的疗效

Jacob, S; Mayer, E L; Kacik, N; Storniolo, A M; Isaacs, C; Mayer, I; Stearns, V; Nanda, R; Nangia, J; Chien, A J; Moasser, M; Melisko, M; Wabl, C; Muzikansky, A; Geradts, J; Dillon, D A; Park, B H; Krop, I; Wolff, A C; Kochupurakkal, B; Shapiro, G I; Rugo, H S

Spatially Discontinuous Mutation Topographies in Ductal Carcinoma In Situ Reveal Noncompetitive Growth Dynamics

导管原位癌中空间不连续的突变地形揭示了非竞争性生长动力学

Ryser, Marc D; Greenwald, Matthew A; Monyak, Daniel; Sorribes, Inmaculada C; King, Lorraine; Hall, Allison; Geradts, Joseph; Weaver, Donald L; Mallo, Diego; Holloway, Shannon T; Wu, Ethan; Murgas, Kevin A; West, Robert B; Grimm, Lars J; Maley, Carlo C; Marks, Jeffrey R; Shibata, Darryl; Hwang, E Shelley

Computational Pathology Detection of Hypoxia-Induced Morphologic Changes in Breast Cancer

计算病理学检测乳腺癌缺氧诱导的形态学变化

Manescu, Petru; Geradts, Joseph; Fernandez-Reyes, Delmiro

Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation

雄激素剥夺通过HGF和Wnt激活,导致异常的核输出和核糖体生物合成,从而诱发双缺失型前列腺癌。

Won Kyung Kim # ,Alyssa J Buckley # ,Dong-Hoon Lee ,Alex Hiroto ,Christian H Nenninger ,Adam W Olson ,Jinhui Wang ,Zhuo Li ,Rajeev Vikram ,Yao Mawulikplimi Adzavon ,Tak-Yu Yau ,Yigang Bao ,Michael Kahn ,Joseph Geradts ,Guang-Qian Xiao ,Zijie Sun

XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant

XIAP 过表达的炎性乳腺癌患者体内免疫抑制细胞亚群浸润程度高,且 TNFR1 信号通路增强,而 Birinapant 可作为靶点治疗这些疾病。

Christophe Van Berckelaer ,Steven Van Laere ,Seayoung Lee ,Michael A Morse ,Joseph Geradts ,Luc Dirix ,Mark Kockx ,François Bertucci ,Peter Van Dam ,Gayathri R Devi

Predicting early breast cancer recurrence from histopathological images in the Carolina Breast Cancer Study

在卡罗莱纳乳腺癌研究中,通过组织病理学图像预测早期乳腺癌复发

Shi, Yifeng; Olsson, Linnea T; Hoadley, Katherine A; Calhoun, Benjamin C; Marron, J S; Geradts, Joseph; Niethammer, Marc; Troester, Melissa A

Reproducibility and intratumoral heterogeneity of the PAM50 breast cancer assay

PAM50 乳腺癌检测的可重复性和肿瘤内异质性

Amber N Hurson, Alina M Hamilton, Linnea T Olsson, Erin L Kirk, Mark E Sherman, Benjamin C Calhoun, Joseph Geradts, Melissa A Troester

Growth Dynamics of Ductal Carcinoma in Situ Recapitulate Normal Breast Development

导管原位癌的生长动力学重现了正常乳腺发育过程。

Ryser, Marc D; Greenwald, Matthew A; Sorribes, Inmaculada C; King, Lorraine M; Hall, Allison; Geradts, Joseph; Weaver, Donald L; Mallo, Diego; Holloway, Shannon; Monyak, Daniel; Gumbert, Graham; Vaez-Ghaemi, Shariar; Wu, Ethan; Murgas, Kevin; Grimm, Lars J; Maley, Carlo C; Marks, Jeffrey R; Shibata, Darryl; Hwang, E Shelley

Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma

单个导管原位癌病变的基因表达特征可识别与浸润性导管癌进展相关的过程和生物标志物

Clare A Rebbeck #, Jian Xian #, Susanne Bornelöv, Joseph Geradts, Amy Hobeika, Heather Geiger, Jose Franco Alvarez, Elena Rozhkova, Ashley Nicholls, Nicolas Robine, Herbert K Lyerly, Gregory J Hannon

Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis

基质雄激素信号作为肿瘤微环境驱动前列腺基底上皮祖细胞引发的癌变

Alex Hiroto #, Won Kyung Kim #, Ariana Pineda, Yongfeng He, Dong-Hoon Lee, Vien Le, Adam W Olson, Joseph Aldahl, Christian H Nenninger, Alyssa J Buckley, Guang-Qian Xiao, Joseph Geradts, Zijie Sun