日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PIGA Mutations and Glycosylphosphatidylinositol Anchor Dysregulation in Polyposis-Associated Duodenal Tumorigenesis

PIGA 突变和糖基磷脂酰肌醇锚定失调与息肉病相关的十二指肠肿瘤发生

Elena Meuser, Kyle Chang, Angharad Walters, Joanna J Hurley, Hannah D West, Iain Perry, Matthew Mort, Laura Reyes-Uribe, Rebekah Truscott, Nicholas Jones, Rachel Lawrence, Gareth Jenkins, Peter Giles, Sunil Dolwani, Bilal Al-Sarireh, Neil Hawkes, Emma Short, Geraint T Williams, Melissa W Taggart, Ki

Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation

Mbd2 能够促进肠道肿瘤的发生,同时抑制促进肿瘤发生的炎症反应。

May, Stephanie; Owen, Heather; Phesse, Toby J; Greenow, Kirsty R; Jones, Gareth-Rhys; Blackwood, Adam; Cook, Peter C; Towers, Christopher; Gallimore, Awen M; Williams, Geraint T; Stürzl, Michael; Britzen-Laurent, Nathalie; Sansom, Owen J; MacDonald, Andrew S; Bird, Adrian P; Clarke, Alan R; Parry, Lee

Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis

Lect2 缺乏的特征是细胞因子水平改变和促进肠道肿瘤发生

Kirsty R Greenow, Matthew Zverev, Stephanie May, Howard Kendrick, Geraint T Williams, Toby Phesse, Lee Parry

Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes

家族性腺瘤性息肉病和MUTYH相关性息肉病中的腺瘤发展:体细胞图谱和驱动基因

Rashid, Mamunur; Fischer, Andrej; Wilson, Cathy H; Tiffen, Jessamy; Rust, Alistair G; Stevens, Philip; Idziaszczyk, Shelley; Maynard, Julie; Williams, Geraint T; Mustonen, Ville; Sampson, Julian R; Adams, David J

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer

Brachyury 鉴定出正常人类肠隐窝和结直肠癌中的一类肠内分泌细胞

Jana Jezkova, Jason S Williams, Filipe Pinto, Stephen J Sammut, Geraint T Williams, Simon Gollins, Ramsay J McFarlane, Rui Manuel Reis, Jane A Wakeman

High endothelial venules are rare in colorectal cancers but accumulate in extra-tumoral areas with disease progression

高内皮静脉在结直肠癌中较为罕见,但随着疾病进展会在肿瘤外区域积聚。

Bento, Diana Costa; Jones, Emma; Junaid, Syed; Tull, Justyna; Williams, Geraint T; Godkin, Andrew; Ager, Ann; Gallimore, Awen

Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer

PI3K 和 MEK 抑制剂在结直肠癌基因定义模型中的体内活性评估

Meera Raja, Matt Zverev, Katja Seipel, Geraint T Williams, Alan R Clarke, Paul H S Shaw