日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists

型抗体工程可以对生物治疗受体激动剂进行构象调节

Matthew G Romei #, Brandon Leonard #, Zachary B Katz, Daniel Le, Yanli Yang, Eric S Day, Christopher W Koo, Preeti Sharma, Jack Bevers Iii, Ingrid Kim, Huiguang Dai, Farzam Farahi, May Lin, Andrey S Shaw, Gerald Nakamura, Jonathan T Sockolosky, Greg A Lazar

An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases

一种用于治疗慢性炎症性疾病的激动性抗信号调节蛋白α抗体

Markus M Xie,Bingbing Dai,Jason A Hackney,Tianhe Sun,Juan Zhang,Janet K Jackman,Surinder Jeet,Ricardo A Irizarry-Caro,Yongyao Fu,Yuxin Liang,Hannah Bender,Eliah R Shamir,Mary E Keir,Jack Bevers,Gerald Nakamura,Michael J Townsend,David A Fox,Alexis Scherl,Wyne P Lee,Flavius Martin,Paul J Godowski,Rajita Pappu,Tangsheng Yi

Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development

开发超灵敏的人类 IL-33 生物标志物检测方法,用于老年性黄斑变性和哮喘药物开发

Elaine Mai, Joyce Chan, Levina Goon, Braeden K Ego, Jack Bevers, Tiffany Wong, Manda Wong, Racquel Corpuz, Hongkang Xi, Jia Wu, Kellen Schneider, Dhaya Seshasayee, Michele Grimbaldeston, Gerald Nakamura, Vahan B Indjeian, Menno van Lookeren Campagne, Kelly M Loyet, Laetitia Comps-Agrar

Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD

大量抗体发现用于探索必需外膜蛋白 LptD 的结构-功能关系

Kelly M Storek, Joyce Chan, Rajesh Vij, Nancy Chiang, Zhonghua Lin, Jack Bevers 3rd, Christopher M Koth, Jean-Michel Vernes, Y Gloria Meng, JianPing Yin, Heidi Wallweber, Olivier Dalmas, Stephanie Shriver, Christine Tam, Kellen Schneider, Dhaya Seshasayee, Gerald Nakamura, Peter A Smith, Jian Payand

Automated high throughput microscale antibody purification workflows for accelerating antibody discovery

自动化高通量微尺度抗体纯化工作流程,加速抗体发现

Peng Luan, Sophia Lee, Tia A Arena, Maciej Paluch, Joe Kansopon, Sharon Viajar, Zahira Begum, Nancy Chiang, Gerald Nakamura, Philip E Hass, Athena W Wong, Greg A Lazar, Avinash Gill

Molecular characterization of human anti-hinge antibodies derived from single-cell cloning of normal human B cells

源自正常人类 B 细胞单细胞克隆的人类抗铰链抗体的分子表征

Tao Huang, Mary Mathieu, Sophia Lee, Xinhua Wang, Yee Seir Kee, Jack J Bevers 3rd, Claudio Ciferri, Alberto Estavez, Manda Wong, Nancy Y Chiang, Gerald Nakamura, Randall J Brezski

A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action

一种具有广泛保护作用的治疗性抗体,可对抗乙型流感病毒,具有两种作用机制

Ning Chai, Lee R Swem, Summer Park, Gerald Nakamura, Nancy Chiang, Alberto Estevez, Rina Fong, Lynn Kamen, Elviza Kho, Mike Reichelt, Zhonghua Lin, Henry Chiu, Elizabeth Skippington, Zora Modrusan, Jeremy Stinson, Min Xu, Patrick Lupardus, Claudio Ciferri, Man-Wah Tan

De Novo MS/MS Sequencing of Native Human Antibodies

人类天然抗体的 De Novo MS/MS 测序

Adrian Guthals, Yutian Gan, Laura Murray, Yongmei Chen, Jeremy Stinson, Gerald Nakamura, Jennie R Lill, Wendy Sandoval, Nuno Bandeira

A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection

中和抗 gH/gL 单克隆抗体对先天性 CMV 感染的豚鼠模型具有保护作用

Marcy R Auerbach, Donghong Yan, Rajesh Vij, Jo-Anne Hongo, Gerald Nakamura, Jean-Michel Vernes, Y Gloria Meng, Samantha Lein, Pamela Chan, Jed Ross, Richard Carano, Rong Deng, Nicholas Lewin-Koh, Min Xu, Becket Feierbach

Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis

通过体内蛋白质组学分析确定耐甲氧西林金黄色葡萄球菌的潜在治疗靶点

Binh An Diep, Qui Phung, Shailesh Date, David Arnott, Corey Bakalarski, Min Xu, Gerald Nakamura, Danielle L Swem, Mary Kate Alexander, Hoan N Le, Thuy T Mai, Man-Wah Tan, Eric J Brown, Mireille Nishiyama