日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults

一项针对健康未感染 HIV 的非洲成年人的佐剂 HIV-1 Gag-Pol-Nef 融合蛋白和腺病毒 35 Gag-RT-Int-Nef 疫苗的安全性和免疫原性的 I 期双盲、安慰剂对照、随机研究

Gloria Omosa-Manyonyi, Juliet Mpendo, Eugene Ruzagira, William Kilembe, Elwyn Chomba, François Roman, Patricia Bourguignon, Marguerite Koutsoukos, Alix Collard, Gerald Voss, Dagna Laufer, Gwynn Stevens, Peter Hayes, Lorna Clark, Emmanuel Cormier, Len Dally, Burc Barin, Jim Ackland, Kristen Syvertsen

Heterologous protection elicited by candidate monomeric recombinant HIV-1 gp120 vaccine in the absence of cross neutralising antibodies in a macaque model

在没有交叉中和抗体的情况下,候选单体重组 HIV-1 gp120 疫苗在猕猴模型中引发异源保护

Mark Page, Richard Stebbings, Neil Berry, Robin Hull, Deborah Ferguson, Leanne Davis, Laura Duffy, William Elsley, Joanna Hall, Claire Ham, Mark Hassall, Bo Li, Edward T Mee, Ruby Quartey-Papafio, Nicola J Rose, Nathalie Mathy, Gerald Voss, E James Stott, Neil Almond

Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site

HIV-1 gp120 的结构稳定化增强了对诱导的辅助受体结合位点的体液免疫反应

Barna Dey, Krisha Svehla, Ling Xu, Dianne Wycuff, Tongqing Zhou, Gerald Voss, Adhuna Phogat, Bimal K Chakrabarti, Yuxing Li, George Shaw, Peter D Kwong, Gary J Nabel, John R Mascola, Richard T Wyatt

Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein

人类免疫缺陷病毒 1 型包膜蛋白三聚体对恒河猴的免疫以及病毒载体或稳定核心蛋白引发的影响

Andreas Mörner, Iyadh Douagi, Mattias N E Forsell, Christopher Sundling, Pia Dosenovic, Sijy O'Dell, Barna Dey, Peter D Kwong, Gerald Voss, Rigmor Thorstensson, John R Mascola, Richard T Wyatt, Gunilla B Karlsson Hedestam

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4

内源性灵长类动物 CD4 改变了 B 细胞对保守的 HIV-1 共受体结合位点的识别

Mattias N E Forsell, Barna Dey, Andreas Mörner, Krisha Svehla, Sijy O'dell, Carl-Magnus Högerkorp, Gerald Voss, Rigmor Thorstensson, George M Shaw, John R Mascola, Gunilla B Karlsson Hedestam, Richard T Wyatt