Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model
通过光遗传学靶向GABA能神经元恢复睡眠,可重编程小胶质细胞并改善阿尔茨海默病模型中的病理表型。
期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-023-00682-9
Zhao, Qiuchen; Maci, Megi; Miller, Morgan R; Zhou, Heng; Zhang, Fang; Algamal, Moustafa; Lee, Yee Fun; Hou, Steven S; Perle, Stephen J; Le, Hoang; Russ, Alyssa N; Lo, Eng H; Gerashchenko, Dmitry; Gomperts, Stephen N; Bacskai, Brian J; Kastanenka, Ksenia V