文献库，生知库 | 链接生命科学的每一步

Bansard Lucile, Laconde Guillaume, Delfosse Vanessa, Huet Tiphaine, Ayeul Margaux, Rigal Emilie, Donati Quentin, Gerbal-Chaloin Sabine, Daujat-Chavanieu Martine, Brunel Luc, Legrand Baptiste, Chavanieu Alain, Martin Anthony R, Pannequin Julie, Bourguet William, Amblard Muriel, Pascussi Jean Marc

肿瘤

肠癌

肿瘤免疫

发表日期：2025

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Omega-3 Fatty Acids, Furan Fatty Acids, and Hydroxy Fatty Acid Esters: Dietary Bioactive Lipids with Potential Benefits for MAFLD and Liver Health

ω-3脂肪酸、呋喃脂肪酸和羟基脂肪酸酯：对代谢相关脂肪肝和肝脏健康具有潜在益处的膳食生物活性脂质

期刊:Nutrients

影响因子:5

doi:10.3390/nu17061031

Merheb, Camil; Gerbal-Chaloin, Sabine; Casas, François; Diab-Assaf, Mona; Daujat-Chavanieu, Martine; Feillet-Coudray, Christine

Therapeutic Plasma Exchange Shows Greater Efficacy Than DFPP in Reducing FT3 and FT4 Levels in Thyrotoxicosis due to Amiodarone-Induced Thyrotoxicosis Type 2

治疗性血浆置换在降低胺碘酮诱导的2型甲状腺毒症患者的FT3和FT4水平方面比DFPP更有效

期刊:Journal of Clinical Apheresis

影响因子:2.7

doi:10.1002/jca.70056

Gerbal, Marion; Gilly, Olivier; Joyeux, Marie-Alix; Moranne, Olivier

免疫/内分泌

发表日期：2025

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On the Possible Effect of Phytic Acid (Myo-Inositol Hexaphosphoric Acid, IP6) on Cytochromes P450 and Systems of Xenobiotic Metabolism in Different Hepatic Models

植酸（肌醇六磷酸，IP6）对不同肝脏模型中细胞色素P450和外源性物质代谢系统的可能影响

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms25073610

Frybortova, Veronika; Satka, Stefan; Jourova, Lenka; Zapletalova, Iveta; Srejber, Martin; Briolotti, Philippe; Daujat-Chavanieu, Martine; Gerbal-Chaloin, Sabine; Anzenbacher, Pavel; Otyepka, Michal; Anzenbacherova, Eva

Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring

间充质干细胞的线粒体转移通过代谢重组赋予胶质母细胞瘤干细胞化学抗性

期刊:Cancer Research Communications

影响因子:2

doi:10.1158/2767-9764.CRC-23-0144

Jean Nakhle, Khattar Khattar, Tülin Özkan, Adel Boughlita, Daouda Abba Moussa, Amélie Darlix, Frédérique Lorcy, Valérie Rigau, Luc Bauchet, Sabine Gerbal-Chaloin, Martine Daujat-Chavanieu, Floriant Bellvert, Laurent Turchi, Thierry Virolle, Jean-Philippe Hugnot, Nicolas Buisine, Mireille Galloni, Va

Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation

葡萄糖饥饿或丙酮酸脱氢酶激活可诱导广泛的 ERK5 介导的代谢重塑，从而导致脂肪酸氧化

期刊:Cells

影响因子:5.1

doi:10.3390/cells11091392

Abrar Ul Haq Khan, Hamideh Salehi, Catherine Alexia, Jose M Valdivielso, Milica Bozic, Isabel C Lopez-Mejia, Lluis Fajas, Sabine Gerbal-Chaloin, Martine Daujat-Chavanieu, Delphine Gitenay, Martin Villalba

Primary hepatocytes isolated from human and porcine donors display similar patterns of cytochrome p450 expression following exposure to prototypical activators of AhR, CAR and PXR

从人类和猪供体分离的原代肝细胞在暴露于 AhR、CAR 和 PXR 的典型激活剂后显示出相似的细胞色素 p450 表达模式

期刊:Current Research in Toxicology

影响因子:2.9

doi:10.1016/j.crtox.2021.03.002

Sabine Gerbal-Chaloin, Philippe Briolotti, Martine Daujat-Chavanieu, Martin Krøyer Rasmussen

The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids

3'-非翻译区导致孕烷 X 受体 (PXR) 表达因 PXR 配体下调和因糖皮质激素上调

期刊:Acta Pharmaceutica Sinica B

影响因子:14.7

doi:10.1016/j.apsb.2019.09.010

Tomas Smutny, Jan Dusek, Lucie Hyrsova, Jana Nekvindova, Alzbeta Horvatova, Stanislav Micuda, Sabine Gerbal-Chaloin, Petr Pavek

信号转导

发表日期：2020

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ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

成年肝细胞中的 ARID1A 缺失激活 β-catenin 介导的促红细胞生成素转录

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.53550

Rozenn Riou, Meriem Ladli, Sabine Gerbal-Chaloin, Pascale Bossard, Angélique Gougelet, Cécile Godard, Robin Loesch, Isabelle Lagoutte, Franck Lager, Julien Calderaro, Alexandre Dos Santos, Zhong Wang, Frédérique Verdier, Sabine Colnot

Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain

地西泮通过与配体结合域直接相互作用促进人类组成型雄烷受体 (CAR) 的易位

期刊:Cells

影响因子:5.1

doi:10.3390/cells9122532

Josef Skoda, Jan Dusek, Martin Drastik, Alzbeta Stefela, Klara Dohnalova, Karel Chalupsky, Tomas Smutny, Stanislav Micuda, Sabine Gerbal-Chaloin, Petr Pavek

Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapse.

利用强效激动剂靶向孕烷X受体的PROTAC疗法延缓结肠癌复发

Omega-3 Fatty Acids, Furan Fatty Acids, and Hydroxy Fatty Acid Esters: Dietary Bioactive Lipids with Potential Benefits for MAFLD and Liver Health

ω-3脂肪酸、呋喃脂肪酸和羟基脂肪酸酯：对代谢相关脂肪肝和肝脏健康具有潜在益处的膳食生物活性脂质

Therapeutic Plasma Exchange Shows Greater Efficacy Than DFPP in Reducing FT3 and FT4 Levels in Thyrotoxicosis due to Amiodarone-Induced Thyrotoxicosis Type 2

治疗性血浆置换在降低胺碘酮诱导的2型甲状腺毒症患者的FT3和FT4水平方面比DFPP更有效

On the Possible Effect of Phytic Acid (Myo-Inositol Hexaphosphoric Acid, IP6) on Cytochromes P450 and Systems of Xenobiotic Metabolism in Different Hepatic Models

植酸（肌醇六磷酸，IP6）对不同肝脏模型中细胞色素P450和外源性物质代谢系统的可能影响

Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring

间充质干细胞的线粒体转移通过代谢重组赋予胶质母细胞瘤干细胞化学抗性

Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation

葡萄糖饥饿或丙酮酸脱氢酶激活可诱导广泛的 ERK5 介导的代谢重塑，从而导致脂肪酸氧化

Primary hepatocytes isolated from human and porcine donors display similar patterns of cytochrome p450 expression following exposure to prototypical activators of AhR, CAR and PXR

从人类和猪供体分离的原代肝细胞在暴露于 AhR、CAR 和 PXR 的典型激活剂后显示出相似的细胞色素 p450 表达模式

The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids

3'-非翻译区导致孕烷 X 受体 (PXR) 表达因 PXR 配体下调和因糖皮质激素上调

ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

成年肝细胞中的 ARID1A 缺失激活 β-catenin 介导的促红细胞生成素转录

Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain

地西泮通过与配体结合域直接相互作用促进人类组成型雄烷受体 (CAR) 的易位