日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis.

中性粒细胞胞外陷阱基因表达特征可识别预后和可靶向的信号通路，用于抑制胰腺肿瘤转移

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-08440-x
McDonald Paul C, Topham James T, Awrey Shannon, Tavakoli Hossein, Carroll Rebekah, Brown Wells S, Gerbec Zachary J, Kalloger Steve E, Karasinska Joanna M, Tang Patricia, Goodwin Rachel, Jones Steven J M, Laskin Janessa, Marra Marco A, Morin Gregg B, Renouf Daniel J, Schaeffer David F, Dedhar Shoukat
信号转导
细胞生物学
肿瘤
中性粒细胞
发表日期：2025
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Identification of intratumoral bacteria that enhance breast tumor metastasis

鉴定促进乳腺肿瘤转移的肿瘤内细菌

期刊:mBio
影响因子:4.7
doi:10.1128/mbio.03595-24
Gerbec, Zachary J; Serapio-Palacios, Antonio; Metcalfe-Roach, Avril; Krekhno, Zakhar; Bar-Yoseph, Haggai; Woodward, Sarah E; Pena-Díaz, Jorge; Nemirovsky, Oksana; Awrey, Shannon; Moreno, Sebastian H; Beatty, Sean; Kong, Esther; Radisavljevic, Nina; Cirstea, Mihai; Chafe, Shawn; McDonald, Paul C; Aparicio, Sam; Finlay, B Brett; Dedhar, Shoukat
微生物学
肿瘤
肿瘤免疫
发表日期：2025
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A Murine Model of Maternal Micronutrient Deficiencies and Gut Inflammatory Host-microbe Interactions in the Offspring

母体微量营养素缺乏和子代肠道炎症宿主-微生物相互作用的小鼠模型

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2024.01.018
Ravi Holani ，Paula T Littlejohn ，Karlie Edwards ，Charisse Petersen ，Kyung-Mee Moon ，Richard G Stacey ，Tahereh Bozorgmehr ，Zachary J Gerbec ，Antonio Serapio-Palacios ，Zakhar Krekhno ，Katherine Donald ，Leonard J Foster ，Stuart E Turvey ，B Brett Finlay
肠炎
炎症
微生物学
炎症/感染
发表日期：2024
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A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells

碳酸酐酶 IX/SLC1A5 轴调节缺氧肿瘤细胞中谷氨酰胺代谢依赖性铁死亡

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-23-0041
Geetha Venkateswaran, Paul C McDonald, Shawn C Chafe, Wells S Brown, Zachary J Gerbec, Shannon J Awrey, Seth J Parker, Shoukat Dedhar
代谢
细胞生物学
肿瘤
肿瘤细胞
FCM
IF
IHC-P
WB
发表日期：2023
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Syntaxin4-Munc18c Interaction Promotes Breast Tumor Invasion and Metastasis by Regulating MT1-MMP Trafficking

Syntaxin4-Munc18c 相互作用通过调节 MT1-MMP 运输促进乳腺肿瘤侵袭和转移

期刊:Molecular Cancer Research
影响因子:4.1
doi:10.1158/1541-7786.MCR-20-0527
Megan I Brasher #, Shawn C Chafe #, Paul C McDonald, Oksana Nemirovsky, Genya Gorshtein, Zachary J Gerbec, Wells S Brown, Olivia R Grafinger, Matthew Marchment, Esther Matus, Shoukat Dedhar, Marc G Coppolino
肿瘤
乳腺癌
FCM
IF
IHC-P
WB
发表日期：2022
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Conditional Deletion of PGC-1α Results in Energetic and Functional Defects in NK Cells

条件性敲除PGC-1α会导致NK细胞能量代谢和功能缺陷

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2020.101454
Gerbec, Zachary J; Hashemi, Elaheh; Nanbakhsh, Arash; Holzhauer, Sandra; Yang, Chao; Mei, Ao; Tsaih, Shirng-Wern; Lemke, Angela; Flister, Michael J; Riese, Matthew J; Thakar, Monica S; Malarkannan, Subramaniam
代谢
细胞生物学
发表日期：2020
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Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses

CD36信号通路介导的线粒体代谢重编程驱动巨噬细胞炎症反应

期刊:Circulation Research
影响因子:16.2
doi:10.1161/CIRCRESAHA.119.315833
Chen, Yiliang; Yang, Moua; Huang, Wenxin; Chen, Wenjing; Zhao, Yiqiong; Schulte, Marie L; Volberding, Peter; Gerbec, Zachary; Zimmermann, Michael T; Zeighami, Atefeh; Demos, Wendy; Zhang, Jue; Knaack, Darcy A; Smith, Brian C; Cui, Weiguo; Malarkannan, Subramaniam; Sodhi, Komal; Shapiro, Joseph I; Xie, Zijian; Sahoo, Daisy; Silverstein, Roy L
巨噬细胞
炎症
CD36
炎症/感染
信号转导
巨噬细胞
代谢
CD3
代谢重编程
线粒体
细胞生物学
免疫/内分泌
发表日期：2019
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Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

通过单细胞转录组学定义人类骨髓和血液自然杀伤细胞的异质性

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-019-11947-7
Chao Yang ，Jason R Siebert ，Robert Burns ，Zachary J Gerbec ，Benedetta Bonacci ，Amy Rymaszewski ，Mary Rau ，Matthew J Riese ，Sridhar Rao ，Karen-Sue Carlson ，John M Routes ，James W Verbsky ，Monica S Thakar ，Subramaniam Malarkannan
细胞生物学
单细胞
自然杀伤细胞
发表日期：2019
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IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells

IQ 结构域 GTPase 活化蛋白 1 调节细胞骨架重组并促进 NKG2D 介导的雷帕霉素复合物 1 激活和自然杀伤细胞中细胞因子基因翻译的机制靶点

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2018.01168
Alex M Abel, Aradhana A Tiwari, Zachary J Gerbec, Jason R Siebert, Chao Yang, Nathan J Schloemer, Kate J Dixon, Monica S Thakar, Subramaniam Malarkannan
免疫
细胞生物学
自然杀伤细胞
mTOR
发表日期：2018
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Cutting Edge: Check Your Mice-A Point Mutation in the Ncr1 Locus Identified in CD45.1 Congenic Mice with Consequences in Mouse Susceptibility to Infection

前沿研究：检查你的小鼠——在CD45.1同源小鼠中发现Ncr1基因座的点突变，该突变会影响小鼠对感染的易感性

期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.1701676
Jang, Youngsoon; Gerbec, Zachary J; Won, Taejoon; Choi, Bongkum; Podsiad, Amy; B Moore, Bethany; Malarkannan, Subramaniam; Laouar, Yasmina
Mouse
发表日期：2018
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