日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In vaccinated individuals serum bactericidal activity against B meningococci is abrogated by C5 inhibition but not by inhibition of the alternative complement pathway

在接种疫苗的个体中,血清对脑膜炎球菌的杀菌活性因 C5 抑制而消失,但因替代补体途径抑制而消失

Emma Ispasanie, Lukas Muri, Marc Schmid, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke

Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity

肌内酯抑制 SEC61 转运蛋白可诱导由 EIF2S1 依赖性翻译控制的保护性自噬反应,而这种反应不需要 ULK1 活性

Belinda S Hall, Scott J Dos Santos, Louise Tzung-Harn Hsieh, Maria Manifava, Marie-Thérèse Ruf, Gerd Pluschke, Nicholas Ktistakis, Rachel E Simmonds

Inhibition of the different complement pathways has varying impacts on the serum bactericidal activity and opsonophagocytosis against Haemophilus influenzae type b

抑制不同的补体途径对b型流感嗜血杆菌血清杀菌活性和调理吞噬作用有不同的影响

Lukas Muri, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke, Emma Ispasanie

Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions

异常的基质组织因子定位和肌内酯驱动的血管功能障碍(因 IL-1β 而加剧)与布鲁里溃疡病变中的纤维蛋白形成有关

Louise Tzung-Harn Hsieh, Scott J Dos Santos, Belinda S Hall, Joy Ogbechi, Aloysius D Loglo, Francisco Javier Salguero, Marie-Thérèse Ruf, Gerd Pluschke, Rachel E Simmonds

Scalable Process for High-Yield Production of Pf CyRPA Using Insect Cells for Inclusion in a Malaria Virosome-Based Vaccine Candidate

利用昆虫细胞高产生产 Pf CyRPA 的可扩展工艺,用于纳入基于疟疾病毒体的疫苗候选物

Bárbara Fernandes, Marcos Sousa, Rute Castro, Anja Schäfer, Julia Hauser, Kai Schulze, Mario Amacker, Marco Tamborrini, Gerd Pluschke, Paula M Alves, Sylvain Fleury, António Roldão

Alternative Complement Pathway Inhibition Abrogates Pneumococcal Opsonophagocytosis in Vaccine-Naïve, but Not in Vaccinated Individuals

替代补体途径抑制可消除未接种疫苗个体的肺炎球菌调理吞噬作用,但对接种疫苗的个体则无影响

Lukas Muri, Emma Ispasanie, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke

Alternative Complement Pathway Inhibition Does Not Abrogate Meningococcal Killing by Serum of Vaccinated Individuals

替代补体途径抑制并不能消除接种疫苗个体血清对脑膜炎球菌的杀灭作用

Emma Ispasanie, Lukas Muri, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke

The cell surface protein MUL_3720 confers binding of the skin pathogen Mycobacterium ulcerans to sulfated glycans and keratin

细胞表面蛋白 MUL_3720 使皮肤病原体溃疡分枝杆菌与硫酸化聚糖和角蛋白结合

Christopher J Day, Katharina Röltgen, Gerd Pluschke, Michael P Jennings

Spontaneous point mutations in the capsule synthesis locus leading to structural and functional changes of the capsule in serogroup A meningococcal populations

荚膜合成位点的自发点突变导致 A 群脑膜炎球菌群荚膜的结构和功能发生变化

Emma Ispasanie, Francesca Micoli, Araceli Lamelas, Dominique Keller, Francesco Berti, Riccardo De Riccio, Roberta Di Benedettoi, Simona Rondini, Gerd Pluschke

Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

疟疾疫苗候选抗原 CyRPA 及其与寄生虫侵袭抑制抗体的复合物的结构

Paola Favuzza, Elena Guffart, Marco Tamborrini, Bianca Scherer, Anita M Dreyer, Arne C Rufer, Johannes Erny, Joerg Hoernschemeyer, Ralf Thoma, Georg Schmid, Bernard Gsell, Araceli Lamelas, Joerg Benz, Catherine Joseph, Hugues Matile, Gerd Pluschke, Markus G Rudolph