日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Facile Protocol for C(sp(2))-C(sp(3)) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

一种用于功能化E3连接酶配体的C(sp(2))-C(sp(3))键形成反应的简便方案

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.202500929
Maksutova, Anita; Geiger, Thomas M; Cianni, Lorenzo; Pieńkowska, Dominika E; Gerhartz, Jan; Read, Lina; Bricelj, Aleša; Herrmann, Alexander; Nelles, Maurice Leon; Ng, Yuen Lam Dora; Hartmann, Marcus D; Krönke, Jan; Sosič, Izidor; Nowak, Radosław P; Gütschow, Michael; Steinebach, Christian
发表日期：2026
文献求助 收藏

Development and Characterization of the First Selective Class IIb Histone Deacetylase Degraders.

首个选择性 IIb 类组蛋白去乙酰化酶降解剂的开发和表征

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00674
Zhai Shiyang, Honin Irina, Schäker-Hübner Linda, Hanl Maria, Jacobi Lukas, Dressler Finn, Pieńkowska Dominika Ewa, König Philipp, Gerhartz Jan, Voget Rabea, Bendas Gerd, Gütschow Michael, Meissner Felix, Burckhardt Bjoern B, Nowak Radosław P, Steinebach Christian, Hansen Finn K
其它
乙酰化
发表日期：2025
文献求助 收藏

Activating p53(Y220C) with a Mutant-Specific Small Molecule.

用突变体特异性小分子激活p53(Y220C)

期刊:
影响因子:
doi:10.1101/2024.10.23.619961
Zhu Xijun, Byun Woong Sub, Pieńkowska Dominika Ewa, Nguyen Kha The, Gerhartz Jan, Geng Qixiang, Qiu Tian, Zhong Jianing, Jiang Zixuan, Wang Mengxiong, Sarott Roman C, Hinshaw Stephen M, Zhang Tinghu, Attardi Laura D, Nowak Radosław P, Gray Nathanael S
信号转导
P53
发表日期：2024
文献求助 收藏