日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Regulated induced proximity targeting chimeras-RIPTACs-A heterobifunctional small molecule strategy for cancer selective therapies.

调控诱导邻近靶向嵌合体-RIPTACs-一种用于癌症选择性治疗的异双功能小分子策略

Raina Kanak, Forbes Chris D, Stronk Rebecca, Rappi Jonathan P Jr, Eastman Kyle J, Zaware Nilesh, Yu Xinheng, Li Hao, Bhardwaj Amit, Gerritz Samuel W, Forgione Mia, Hundt Abigail, King Madeline P, Posner Zoe M, Correia Allison D, McGovern Andrew, Puleo David E, Chenard Rebekka, Mousseau James J, Vergara J Ignacio, Garvin Ethan, Macaluso Jennifer, Martin Michael, Bassoli Kyle, Jones Kelli, Garcia Marco, Howard Katia, Yaggi Madeleine, Smith Levi M, Chen Jinshan M, Mayfield Andrew B, De Leon Cesar A, Hines John, Kayser-Bricker Katherine J, Crews Craig M

SAT516 Impact Of The Braf V600E Gene Mutation In Patients With Papillary Thyroid Cancer From Northern Ecuadorian Andes

SAT516 研究:Braf V600E 基因突变对厄瓜多尔北部安第斯山脉乳头状甲状腺癌患者的影响

Gerritz, Lena; Schervish, Meredith; Lakey, Pascale S J; Oeij, Tim; Wei, Jinlai; Nizkorodov, Sergey A; Shiraiwa, Manabu; Choate, Lauren; Pazdernik, Vanessa; Kollmeyer, Thomas; Praska, Corinne; Jenkins, Robert; Ida, Cristine; Guo, C; Yang, Q; He, Z; Duan, H; Liu, R; Mu, Y; Goett, H; Schön, C; Beusker, P; Uhl, E; Stein, M; Solis Pazmiño, Andrea Paola; Cardenas, Tamara; Cucalon, Jessica; Jaramillo-Koupermann, Gabriela; Galvez, Gabriela; Reyes, Carlos; Vega, Jorge Salazar-

Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively

调节诱导邻近靶向嵌合体 (RIPTAC):一种选择性杀死癌细胞的新型异双功能小分子治疗策略

Kanak Raina, Chris D Forbes, Rebecca Stronk, Jonathan P Rappi Jr, Kyle J Eastman, Samuel W Gerritz, Xinheng Yu, Hao Li, Amit Bhardwaj, Mia Forgione, Abigail Hundt, Madeline P King, Zoe M Posner, Allison Denny, Andrew McGovern, David E Puleo, Ethan Garvin, Rebekka Chenard, Nilesh Zaware, James J Mous

Discovery of Selective Cannabinoid CB(2) Receptor Agonists by High-Throughput Screening

利用高通量筛选发现选择性大麻素CB(2)受体激动剂

Ogawa, Lisa M; Burford, Neil T; Liao, Yu-Hsien; Scott, Caitlin E; Hine, Ashley M; Dowling, Craig; Chin, Jefferson; Power, Mike; Hunnicutt, Edward J Jr; Emerick, Victoria L; Banks, Martyn; Zhang, Litao; Gerritz, Samuel W; Alt, Andrew; Kendall, Debra A

Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor

δ-阿片受体选择性正变构调节剂的发现、合成和分子药理学

Neil T Burford, Kathryn E Livingston, Meritxell Canals, Molly R Ryan, Lauren M L Budenholzer, Ying Han, Yi Shang, John J Herbst, Jonathan O'Connell, Martyn Banks, Litao Zhang, Marta Filizola, Daniel L Bassoni, Tom S Wehrman, Arthur Christopoulos, John R Traynor, Samuel W Gerritz, Andrew Alt

Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315

cdc2 样 (Clk) 和双特异性酪氨酸磷酸化调节 (Dyrk) 激酶的小分子嘧啶抑制剂:化学探针 ML315 的开发

Thomas C Coombs, Cordelle Tanega, Min Shen, Jenna L Wang, Douglas S Auld, Samuel W Gerritz, Frank J Schoenen, Craig J Thomas, Jeffrey Aubé

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

通过诱导形成高级核蛋白寡聚体的小分子抑制流感病毒复制

Gerritz, Samuel W; Cianci, Christopher; Kim, Sean; Pearce, Bradley C; Deminie, Carol; Discotto, Linda; McAuliffe, Brian; Minassian, Beatrice F; Shi, Shuhao; Zhu, Shirong; Zhai, Weixu; Pendri, Annapurna; Li, Guo; Poss, Michael A; Edavettal, Suzanne; McDonnell, Patricia A; Lewis, Hal A; Maskos, Klaus; Mörtl, Mario; Kiefersauer, Reiner; Steinbacher, Stefan; Baldwin, Eric T; Metzler, William; Bryson, James; Healy, Matthew D; Philip, Thomas; Zoeckler, Mary; Schartman, Richard; Sinz, Michael; Leyva-Grado, Victor H; Hoffmann, Hans-Heinrich; Langley, David R; Meanwell, Nicholas A; Krystal, Mark